Dissociation of pulse wave velocity and aortic wall stiffness in diabetic db/db mice: The influence of blood pressure

Dissociation of pulse wave velocity and aortic wall stiffness in diabetic db/db mice: The influence of blood pressure

Introduction: Vascular stiffness is a predictor of cardiovascular disease and pulse wave velocity (PWV) is the current standard for measuring in vivo vascular stiffness. Mean arterial pressure is the largest confounding variable to PWV; therefore, in this study we aimed to test the hypothesis that i...

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Bibliographic Details
Main Authors: Patricia E. McCallinhart, Yong Ung Lee, Avione Lee, Mircea Anghelescu, Jeffrey R. Tonniges, Ed Calomeni, Gunjan Agarwal, Joy Lincoln, Aaron J. Trask
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Physiology
Subjects:
vascular stiffness
pulse wave velocity
hypertension
diabetes
metabolic syndrome
aortic biomechanics
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1154454/full

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