Key events in cancer: Dysregulation of SREBPs

Key events in cancer: Dysregulation of SREBPs

Lipid metabolism reprogramming is an important hallmark of tumor progression. Cancer cells require high levels of lipid synthesis and uptake not only to support their continued replication, invasion, metastasis, and survival but also to participate in the formation of biological membranes and signal...

Full description

Bibliographic Details
Main Authors: Yunkuo Li, Shouwang Wu, Xiaodong Zhao, Shiming Hao, Faping Li, Yuxiong Wang, Bin Liu, Difei Zhang, Yishu Wang, Honglan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
SREBPs
lipid metabolism
fatty acids
cholesterol
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1130747/full

Similar Items

Similar Items