Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate

As part of the circular economy idea, rice straw without additives has been investigated as a way to turn agricultural waste into products with added value. The nutrients in the substrate, Calocybe indica yield, and biological effects were all calculated. In this investigation, the methanol extract...

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Main Authors: Sahithi Somavarapu Thomas Anne, Lakshmi Murugan Kavitha Vijaya, Sekar Jayapriya, Velmurugan Mahalakshmi, Sriariyanun Malinee, Shanmugam Vinodhini
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:E3S Web of Conferences
Subjects:
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/65/e3sconf_ri2c2023_02006.pdf
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author Sahithi Somavarapu Thomas Anne
Lakshmi Murugan Kavitha Vijaya
Sekar Jayapriya
Velmurugan Mahalakshmi
Sriariyanun Malinee
Shanmugam Vinodhini
author_facet Sahithi Somavarapu Thomas Anne
Lakshmi Murugan Kavitha Vijaya
Sekar Jayapriya
Velmurugan Mahalakshmi
Sriariyanun Malinee
Shanmugam Vinodhini
author_sort Sahithi Somavarapu Thomas Anne
collection DOAJ
description As part of the circular economy idea, rice straw without additives has been investigated as a way to turn agricultural waste into products with added value. The nutrients in the substrate, Calocybe indica yield, and biological effects were all calculated. In this investigation, the methanol extract was used. GCMS was examined to discover the necessary compounds present in fungi. A surplus of mushrooms was harvested, and it was discovered that the growth of mushrooms on the rice substrate took place in less than five days. At a humidity of 93%, biological efficiency was determined to be in the range of 54.5-130.9%. In vitro and molecular docking results for the antidiabetic showed good inhibitory properties. As a result, rice straw could be a productive and affordable growing medium for milky mushrooms.
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spelling doaj.art-f3669a50a4574bbb88de97d706db24552023-09-26T10:12:06ZengEDP SciencesE3S Web of Conferences2267-12422023-01-014280200610.1051/e3sconf/202342802006e3sconf_ri2c2023_02006Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable SubstrateSahithi Somavarapu Thomas Anne0Lakshmi Murugan Kavitha Vijaya1Sekar Jayapriya2Velmurugan Mahalakshmi3Sriariyanun Malinee4Shanmugam Vinodhini5Institute of Brain Science (IBS), TICEL BioparkDepartment of Biotechnology, D.K.M College for WomenDepartment of Biotechnology, D.K.M College for WomenDepartment of Biotechnology, D.K.M College for WomenBiorefinery and Process Automation Engineering Center, Department of Chemical and Process Engineering, The Sirindhorn International Thai-German Graduate School of Engineering, King Mongkut’s University of Technology North BangkokDepartment of Biotechnology, D.K.M College for WomenAs part of the circular economy idea, rice straw without additives has been investigated as a way to turn agricultural waste into products with added value. The nutrients in the substrate, Calocybe indica yield, and biological effects were all calculated. In this investigation, the methanol extract was used. GCMS was examined to discover the necessary compounds present in fungi. A surplus of mushrooms was harvested, and it was discovered that the growth of mushrooms on the rice substrate took place in less than five days. At a humidity of 93%, biological efficiency was determined to be in the range of 54.5-130.9%. In vitro and molecular docking results for the antidiabetic showed good inhibitory properties. As a result, rice straw could be a productive and affordable growing medium for milky mushrooms.https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/65/e3sconf_ri2c2023_02006.pdfantidiabetic propertybioactive compoundscalocybe indicacultivationmolecular docking
spellingShingle Sahithi Somavarapu Thomas Anne
Lakshmi Murugan Kavitha Vijaya
Sekar Jayapriya
Velmurugan Mahalakshmi
Sriariyanun Malinee
Shanmugam Vinodhini
Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
E3S Web of Conferences
antidiabetic property
bioactive compounds
calocybe indica
cultivation
molecular docking
title Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
title_full Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
title_fullStr Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
title_full_unstemmed Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
title_short Antidiabetic Activity and Molecular Docking Analysis of Milky Mushroom (Calocybe indica) Grown on the Renewable Substrate
title_sort antidiabetic activity and molecular docking analysis of milky mushroom calocybe indica grown on the renewable substrate
topic antidiabetic property
bioactive compounds
calocybe indica
cultivation
molecular docking
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/65/e3sconf_ri2c2023_02006.pdf
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