Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New <i>N′</i>-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors

Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New <i>N′</i>-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors

Background: Hydrazides play a vital role in making biologically active compounds in various fields of chemistry. These determine antioxidant, antidepressant, antimalarial, anti-inflammatory, antiglycating, and antimicrobial activity. In the present study, twenty-three new <i>N′</i> benzy...

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Bibliographic Details
Main Authors: Sajjad Ahmad, Momin Khan, Najeeb Ur Rehman, Muhammad Ikram, Sadia Rehman, Mahboob Ali, Jalal Uddin, Ajmal Khan, Aftab Alam, Ahmed Al-Harrasi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
synthesis
urease inhibition
4-(tert-butyl)benzohydrazide
crystal structure
in vitro
SAR
Online Access:https://www.mdpi.com/1420-3049/27/20/6906

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