In vivo production of pederin by labrenzin pathway expansion
Pederin is a potent polyketide toxin that causes severe skin lesions in humans after contact with insects of genus Paederus. Due to its potent anticancer activities, pederin family compounds have raised the interest of pharmaceutical industry. Despite the extensive studies on the cluster of biosynth...
Main Authors: | Dina Kačar, Carmen Schleissner, Librada M. Cañedo, Pilar Rodríguez, Fernando de la Calle, Carmen Cuevas, Beatriz Galán, José Luis García |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | Metabolic Engineering Communications |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030122000074 |
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