Vitamin D supplementation to prevent tuberculosis infection in South African schoolchildren: multicenter phase 3 double-blind randomized placebo-controlled trial (ViDiKids)

Vitamin D supplementation to prevent tuberculosis infection in South African schoolchildren: multicenter phase 3 double-blind randomized placebo-controlled trial (ViDiKids)

ABSTRACT: Objectives: To determine whether weekly oral supplementation with 10,000 IU vitamin D3 for 3 years reduces the risk of sensitization to M. tuberculosis in South African schoolchildren aged 6-11 years with negative QuantiFERON-tuberculosis (TB) Gold Plus (QFT-Plus) assay results at baselin...

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Bibliographic Details
Main Authors: Keren Middelkoop, Justine Stewart, Neil Walker, Carmen Delport, David A. Jolliffe, Anna K. Coussens, James Nuttall, Jonathan C.Y. Tang, William D. Fraser, Christopher J. Griffiths, Geeta Trilok Kumar, Suzanne Filteau, Richard L. Hooper, Robert J. Wilkinson, Linda-Gail Bekker, Adrian R. Martineau
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:International Journal of Infectious Diseases
Subjects:
Vitamin D
Tuberculosis
Randomized controlled trial
Interferon-gamma release assay
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223005623

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