Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix

Background Mechanical stimulation of acute ischemic myocardium by shock wave therapy (SWT) is known to improve cardiac function by induction of angiogenesis. However, SWT in chronic heart failure is poorly understood. We aimed to study whether mechanical stimulation upon SWT improves heart function...

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Bibliographic Details
Main Authors: Can Gollmann‐Tepeköylü, Daniela Lobenwein, Markus Theurl, Uwe Primessnig, Daniela Lener, Elke Kirchmair, Wolfgang Mathes, Michael Graber, Leo Pölzl, Angela An, Katarzyna Koziel, Elisabeth Pechriggl, Jakob Voelkl, Patrick Paulus, Wolfgang Schaden, Michael Grimm, Rudolf Kirchmair, Johannes Holfeld
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiogenesis
heparan sulfate proteoglycans
myocardial ischemia
postnatal vasculogenesis
shock wave therapy
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010025

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