Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

Abstract Background As one of the most common chromosomal causes, chromosome translocation leads to T-cell acute lymphoblastic leukemia (T-ALL). Ku70 is one of the key factors of error-prone DNA repair and it may end in translocation. So far, the direct correlation between Ku70 and translocation has...

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Bibliographic Details
Main Authors: Zhenbo Cheng, Yupeng Wang, Lihuang Guo, Jiancheng Li, Wei Zhang, Conghui Zhang, Yangxu Liu, Yue Huang, Keqian Xu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Radiation Oncology
Subjects:
Ku70
Chromosome translocation
Human lymphocytes
Radiation
T-cell acute lymphoblastic leukemia
Radiation damage biomarker
Online Access:https://doi.org/10.1186/s13014-022-02113-3

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