Overexpression of TIMP3 Protects Against Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Apoptosis Through ROS/Mapks Pathway

Overexpression of TIMP3 Protects Against Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Apoptosis Through ROS/Mapks Pathway

Background/Aims: Myocardial ischemia/reperfusion (I/R) injury remains a great challenge in clinical therapy. Tissue inhibitor of metalloproteinases 3 (TIMP3) plays a crucial role in heart physiological and pathophysiological processes. However, the effects of TIMP3 on I/R injury remain unknown. Meth...

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Bibliografiske detaljer
Main Authors: Hui Liu, Xibo Jing, Aiqiao Dong, Baobao Bai, Haiyan Wang
Format: Article
Sprog:English
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Serier:Cellular Physiology and Biochemistry
Fag:
Ischemia/reperfusion injury
Myocardial apoptosis
TIMP3
ROS
MAPKs
Online adgang:https://www.karger.com/Article/FullText/485401

Internet

https://www.karger.com/Article/FullText/485401

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