Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening

Currently, the diagnosis of tuberculosis (TB) is mainly based on the comprehensive consideration of the patient's symptoms and signs, laboratory examinations and chest radiography (CXR). CXR plays a pivotal role to support the early diagnosis of TB, especially when used for TB screening and dif...

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Main Authors: Xue-Fang Cao, Yuan Li, He-Nan Xin, Hao-Ran Zhang, Madhukar Pai, Lei Gao
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Chronic Diseases and Translational Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X21000049
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author Xue-Fang Cao
Yuan Li
He-Nan Xin
Hao-Ran Zhang
Madhukar Pai
Lei Gao
author_facet Xue-Fang Cao
Yuan Li
He-Nan Xin
Hao-Ran Zhang
Madhukar Pai
Lei Gao
author_sort Xue-Fang Cao
collection DOAJ
description Currently, the diagnosis of tuberculosis (TB) is mainly based on the comprehensive consideration of the patient's symptoms and signs, laboratory examinations and chest radiography (CXR). CXR plays a pivotal role to support the early diagnosis of TB, especially when used for TB screening and differential diagnosis. However, high cost of CXR hardware and shortage of certified radiologists poses a major challenge for CXR application in TB screening in resource limited settings. The latest development of artificial intelligence (AI) combined with the accumulation of a large number of medical images provides new opportunities for the establishment of computer-aided detection (CAD) systems in the medical applications, especially in the era of deep learning (DL) technology. Several CAD solutions are now commercially available and there is growing evidence demonstrate their value in imaging diagnosis. Recently, WHO published a rapid communication which stated that CAD may be used as an alternative to human reader interpretation of plain digital CXRs for screening and triage of TB.
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spelling doaj.art-f37a52adb94b47c38c17f6e20fe0ca3f2022-12-22T02:41:52ZengWileyChronic Diseases and Translational Medicine2095-882X2021-03-01713540Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screeningXue-Fang Cao0Yuan Li1He-Nan Xin2Hao-Ran Zhang3Madhukar Pai4Lei Gao5NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, And Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaJF Healthcare, Nanchang, Jiangxi 330072, ChinaNHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, And Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaNHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, And Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaMcGill International TB Centre, McGill University, Montreal, CanadaNHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, And Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; Corresponding author. NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, and Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 9 Dong Dan San Tiao, Dongcheng District, Beijing 100730, China.Currently, the diagnosis of tuberculosis (TB) is mainly based on the comprehensive consideration of the patient's symptoms and signs, laboratory examinations and chest radiography (CXR). CXR plays a pivotal role to support the early diagnosis of TB, especially when used for TB screening and differential diagnosis. However, high cost of CXR hardware and shortage of certified radiologists poses a major challenge for CXR application in TB screening in resource limited settings. The latest development of artificial intelligence (AI) combined with the accumulation of a large number of medical images provides new opportunities for the establishment of computer-aided detection (CAD) systems in the medical applications, especially in the era of deep learning (DL) technology. Several CAD solutions are now commercially available and there is growing evidence demonstrate their value in imaging diagnosis. Recently, WHO published a rapid communication which stated that CAD may be used as an alternative to human reader interpretation of plain digital CXRs for screening and triage of TB.http://www.sciencedirect.com/science/article/pii/S2095882X21000049TuberculosisArtificial intelligenceDigital chest radiographyDiagnosisTriage
spellingShingle Xue-Fang Cao
Yuan Li
He-Nan Xin
Hao-Ran Zhang
Madhukar Pai
Lei Gao
Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
Chronic Diseases and Translational Medicine
Tuberculosis
Artificial intelligence
Digital chest radiography
Diagnosis
Triage
title Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
title_full Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
title_fullStr Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
title_full_unstemmed Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
title_short Application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
title_sort application of artificial intelligence in digital chest radiography reading for pulmonary tuberculosis screening
topic Tuberculosis
Artificial intelligence
Digital chest radiography
Diagnosis
Triage
url http://www.sciencedirect.com/science/article/pii/S2095882X21000049
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