Sexual rejection via a vomeronasal receptor-triggered limbic circuit
Sex pheromones that increase mating have been reported across a number of different species, yet there is little known about pheromones that suppress female mating drive. This study reports that juvenile female mice release a pheromone, ESP22, which suppresses sexual receptivity of adult female mice...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07003-5 |
| _version_ | 1819195303903887360 |
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| author | Takuya Osakada Kentaro K. Ishii Hiromi Mori Ryo Eguchi David M. Ferrero Yoshihiro Yoshihara Stephen D. Liberles Kazunari Miyamichi Kazushige Touhara |
| author_facet | Takuya Osakada Kentaro K. Ishii Hiromi Mori Ryo Eguchi David M. Ferrero Yoshihiro Yoshihara Stephen D. Liberles Kazunari Miyamichi Kazushige Touhara |
| author_sort | Takuya Osakada |
| collection | DOAJ |
| description | Sex pheromones that increase mating have been reported across a number of different species, yet there is little known about pheromones that suppress female mating drive. This study reports that juvenile female mice release a pheromone, ESP22, which suppresses sexual receptivity of adult female mice by evoking a robust rejection behavior upon male mounting. |
| first_indexed | 2024-12-23T02:10:37Z |
| format | Article |
| id | doaj.art-f37fab123ab949e592fff408513bdaf2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T02:10:37Z |
| publishDate | 2018-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-f37fab123ab949e592fff408513bdaf22022-12-21T18:03:48ZengNature PortfolioNature Communications2041-17232018-10-019111510.1038/s41467-018-07003-5Sexual rejection via a vomeronasal receptor-triggered limbic circuitTakuya Osakada0Kentaro K. Ishii1Hiromi Mori2Ryo Eguchi3David M. Ferrero4Yoshihiro Yoshihara5Stephen D. Liberles6Kazunari Miyamichi7Kazushige Touhara8Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoDepartment of Cell Biology, Harvard Medical SchoolERATO Touhara Chemosensory Signal Project, JST, The University of TokyoDepartment of Cell Biology, Harvard Medical SchoolDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of TokyoSex pheromones that increase mating have been reported across a number of different species, yet there is little known about pheromones that suppress female mating drive. This study reports that juvenile female mice release a pheromone, ESP22, which suppresses sexual receptivity of adult female mice by evoking a robust rejection behavior upon male mounting.https://doi.org/10.1038/s41467-018-07003-5 |
| spellingShingle | Takuya Osakada Kentaro K. Ishii Hiromi Mori Ryo Eguchi David M. Ferrero Yoshihiro Yoshihara Stephen D. Liberles Kazunari Miyamichi Kazushige Touhara Sexual rejection via a vomeronasal receptor-triggered limbic circuit Nature Communications |
| title | Sexual rejection via a vomeronasal receptor-triggered limbic circuit |
| title_full | Sexual rejection via a vomeronasal receptor-triggered limbic circuit |
| title_fullStr | Sexual rejection via a vomeronasal receptor-triggered limbic circuit |
| title_full_unstemmed | Sexual rejection via a vomeronasal receptor-triggered limbic circuit |
| title_short | Sexual rejection via a vomeronasal receptor-triggered limbic circuit |
| title_sort | sexual rejection via a vomeronasal receptor triggered limbic circuit |
| url | https://doi.org/10.1038/s41467-018-07003-5 |
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