Discovery of Novel Indolealkylpiperazine Derivatives as Potent 5-HT<sub>1A</sub> Receptor Agonists for the Potential Future Treatment of Depression

Discovery of Novel Indolealkylpiperazine Derivatives as Potent 5-HT<sub>1A</sub> Receptor Agonists for the Potential Future Treatment of Depression

Depression is a severe psychiatric disorder that affects over 100 million people worldwide. 5-HT<sub>1A</sub> receptor agonists have been implicated in the treatment of a variety of central nervous system diseases, especially depression. In this study, based on <b>FW01</b>, a...

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Bibliographic Details
Main Authors: Chen Zhu, Xinwei Li, Weiqing Peng, Wei Fu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
5-HT<sub>1A</sub> receptor agonist
depression
drug design
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/25/21/5078

Internet

https://www.mdpi.com/1420-3049/25/21/5078

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