Occult breast cancer. Literature review and case series

Background. Currently, there are several forms of breast cancer (BC): nodular, diffuse, edematous-infiltrative, mastitis-like form, as well as Paget’s cancer. A special form of BC is the hidden or occult form. Taking into account the analysis of methods for the diagnosis and treatment of occult BC,...

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Main Authors: О. S. Khodorovich, V. A. Solodkiy, A. A. Kalinina-Masri, О. Р. Bliznyukov, T. V. Sherstneva, I. A. Lazukina, L. B. Kanakhina
Format: Article
Language:Russian
Published: ABV-press 2021-03-01
Series:Опухоли женской репродуктивной системы
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Online Access:https://ojrs.abvpress.ru/ojrs/article/view/777
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author О. S. Khodorovich
V. A. Solodkiy
A. A. Kalinina-Masri
О. Р. Bliznyukov
T. V. Sherstneva
I. A. Lazukina
L. B. Kanakhina
author_facet О. S. Khodorovich
V. A. Solodkiy
A. A. Kalinina-Masri
О. Р. Bliznyukov
T. V. Sherstneva
I. A. Lazukina
L. B. Kanakhina
author_sort О. S. Khodorovich
collection DOAJ
description Background. Currently, there are several forms of breast cancer (BC): nodular, diffuse, edematous-infiltrative, mastitis-like form, as well as Paget’s cancer. A special form of BC is the hidden or occult form. Taking into account the analysis of methods for the diagnosis and treatment of occult BC, it is important that this form of the disease is detected at a later stage. It includes axillary lymphadenopathy and histologically appears to be a metastatic lesion of the lymph nodes from undetectable invasive BC.Materials and methods. We conducted a thorough analysis of domestic and foreign literature and described two clinical examples with authentic documentation of the results of the examination and treatment. The article describes in detail the schemes of drug treatment and descriptions of the results of morphological examination of the surgical material.Results. Given the complexity of the diagnostic stage, the clinical form of the course of diseases, the described clinical examples can be attributed specifically to the occult form of BC. An important and determining factor in treatment is the diagnostic stage using all possible methods, including positron emission tomography–computed tomography, breast magnetic resonance imaging and trepan-biopsy of regional lymph nodes, followed by the determination of the molecular biological subtype of the tumor.Conclusions. In this article, the presented data confirm the general statement about the uniqueness of this disease, which requires a more detailed and multidisciplinary approach at the stage of diagnosis and determination of treatment tactics.
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spelling doaj.art-f38371ba0057406aaddee49b3163c9d22023-03-13T08:44:37ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272021-03-01164465310.17650/1994-4098-2020-16-4-46-53665Occult breast cancer. Literature review and case seriesО. S. Khodorovich0V. A. Solodkiy1A. A. Kalinina-Masri2О. Р. Bliznyukov3T. V. Sherstneva4I. A. Lazukina5L. B. Kanakhina6ФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииФГБУ «Российский научный центр рентгенорадиологии» Минздрава РоссииBackground. Currently, there are several forms of breast cancer (BC): nodular, diffuse, edematous-infiltrative, mastitis-like form, as well as Paget’s cancer. A special form of BC is the hidden or occult form. Taking into account the analysis of methods for the diagnosis and treatment of occult BC, it is important that this form of the disease is detected at a later stage. It includes axillary lymphadenopathy and histologically appears to be a metastatic lesion of the lymph nodes from undetectable invasive BC.Materials and methods. We conducted a thorough analysis of domestic and foreign literature and described two clinical examples with authentic documentation of the results of the examination and treatment. The article describes in detail the schemes of drug treatment and descriptions of the results of morphological examination of the surgical material.Results. Given the complexity of the diagnostic stage, the clinical form of the course of diseases, the described clinical examples can be attributed specifically to the occult form of BC. An important and determining factor in treatment is the diagnostic stage using all possible methods, including positron emission tomography–computed tomography, breast magnetic resonance imaging and trepan-biopsy of regional lymph nodes, followed by the determination of the molecular biological subtype of the tumor.Conclusions. In this article, the presented data confirm the general statement about the uniqueness of this disease, which requires a more detailed and multidisciplinary approach at the stage of diagnosis and determination of treatment tactics.https://ojrs.abvpress.ru/ojrs/article/view/777рак молочной железыоккультный рак молочной железыиммуногистохимическое исследованиемагнитнорезонансная томография молочных желез
spellingShingle О. S. Khodorovich
V. A. Solodkiy
A. A. Kalinina-Masri
О. Р. Bliznyukov
T. V. Sherstneva
I. A. Lazukina
L. B. Kanakhina
Occult breast cancer. Literature review and case series
Опухоли женской репродуктивной системы
рак молочной железы
оккультный рак молочной железы
иммуногистохимическое исследование
магнитнорезонансная томография молочных желез
title Occult breast cancer. Literature review and case series
title_full Occult breast cancer. Literature review and case series
title_fullStr Occult breast cancer. Literature review and case series
title_full_unstemmed Occult breast cancer. Literature review and case series
title_short Occult breast cancer. Literature review and case series
title_sort occult breast cancer literature review and case series
topic рак молочной железы
оккультный рак молочной железы
иммуногистохимическое исследование
магнитнорезонансная томография молочных желез
url https://ojrs.abvpress.ru/ojrs/article/view/777
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AT vasolodkiy occultbreastcancerliteraturereviewandcaseseries
AT aakalininamasri occultbreastcancerliteraturereviewandcaseseries
AT orbliznyukov occultbreastcancerliteraturereviewandcaseseries
AT tvsherstneva occultbreastcancerliteraturereviewandcaseseries
AT ialazukina occultbreastcancerliteraturereviewandcaseseries
AT lbkanakhina occultbreastcancerliteraturereviewandcaseseries