Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

Proton Beam Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

Purpose: To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). Materials and Methods: A review of the pertinent literature. Results: Proton beam therapy likely results in reduced acute and late toxicity as compared with inte...

Full description

Bibliographic Details
Main Authors: William M. Mendenhall, MD, Jonathan J. Beitler, MD, MBA, Nabil F. Saba, MD, FACP, Ashok R. Shaha, MD, FACS, Sandra Nuyts, MD, PhD, Primož Strojan, MD, Heleen Bollen, MD, Oded Cohen, MD, Robert Smee, MD, Sweet Ping Ng, MD, Avraham Eisbruch, MD, Wai Tong Ng, MD, Jessica M. Kirwan, MA, Alfio Ferlito, MD, DLO, DPath, FRCSEd ad hominem, FRCS (Eng, Glasg, Ir) ad eundem, FDSRCS ad eundem, FACS, FHKCORL, FRCPath, FASCP, IFCAP
Format: Article
Language:English
Published: Particle Therapy Co-operative Group 2023-04-01
Series:International Journal of Particle Therapy
Subjects:
particle therapy
head and neck cancer
oropharynx
cancer outcomes
Online Access:https://theijpt.org/doi/pdf/10.14338/IJPT-22-00030.1
Description
Summary:Purpose: To discuss the role of proton beam therapy (PBT) in the treatment of patients with oropharyngeal squamous cell carcinoma (OPSCC). Materials and Methods: A review of the pertinent literature. Results: Proton beam therapy likely results in reduced acute and late toxicity as compared with intensity-modulated radiation therapy (IMRT). The extent of the reduced toxicity, which may be modest, depends on the endpoint and technical factors such as pencil beam versus passive scattered PBT and adaptive replanning. The disease control rates after PBT are likely similar to those after IMRT. Conclusion: Proton beam therapy is an attractive option to treat patients with OPSCC. Whether it becomes widely available depends on access.
ISSN:2331-5180

Similar Items