IP-10 (CXCL10) Can Trigger Emergence of Dormant Breast Cancer Cells in a Metastatic Liver Microenvironment

IP-10 (CXCL10) Can Trigger Emergence of Dormant Breast Cancer Cells in a Metastatic Liver Microenvironment

Metastatic breast cancer remains a largely incurable and fatal disease with liver involvement bearing the worst prognosis. The danger is compounded by a subset of disseminated tumor cells that may lie dormant for years to decades before re-emerging as clinically detectable metastases. Pathophysiolog...

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Bibliographic Details
Main Authors: Amanda M. Clark, Haley L. Heusey, Linda G. Griffith, Douglas. A. Lauffenburger, Alan Wells
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
metastasis
tumor dormancy
tumor emergence
IP-10
CXCL10
breast cancer dormancy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.676135/full

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