Efficient and Low Cytotoxicity Gene Carriers Based on Amine-Functionalized Polyvinylpyrrolidone

Efficient and Low Cytotoxicity Gene Carriers Based on Amine-Functionalized Polyvinylpyrrolidone

Non-viral vectors are a safety tool for gene therapy to deliver therapeutic genes. Among the different non-viral vectors, polyvinylpyrrolidone (PVP), a well-known hydrosoluble, neutral, and non-toxic polymer, satisfies the requirements and becomes a suitable candidate for gene delivery. In this stud...

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Bibliographic Details
Main Authors:	Anselmo Del Prado, Ana Civantos, Enrique Martínez-Campos, Pavel A. Levkin, Helmut Reinecke, Alberto Gallardo, Carlos Elvira
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Polymers
Subjects:	polyvinylpyrrolidone cationic polymers biomaterials cytocompatibility transfection
Online Access:	https://www.mdpi.com/2073-4360/12/11/2724

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