Adipose-derived cellular therapies prolong graft survival in an allogenic hind limb transplantation model

Adipose-derived cellular therapies prolong graft survival in an allogenic hind limb transplantation model

Abstract Background The long-term survival after vascularized composite allotransplantation (VCA) is often limited by systemic rejection as well as the adverse effects of immunosuppressants. The stromal vascular fraction (SVF) can be expanded to produce adipose-derived stem cells (ADSC) which repres...

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Bibliographic Details
Main Authors: Jingting Chen, Yinmin Wang, Haoyue Hu, Yao Xiong, Shoubao Wang, Jun Yang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Vascularized composite allograft (VCA)
Stromal vascular fraction (SVF)
Immune modulation
Online Access:https://doi.org/10.1186/s13287-021-02162-7

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