Integrated genetic and epigenetic analysis of myxofibrosarcoma

Integrated genetic and epigenetic analysis of myxofibrosarcoma

Myxofibrosarcoma occurs in adults and is associated with high local relapse. Here, based on exome/transcriptome sequencing and DNA methylation analysis, the authors identify driver genes and methylation clusters associated with unique combinations of mutations, outcomes, and immune cell compositions...

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Bibliographic Details
Main Authors: Koichi Ogura, Fumie Hosoda, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Yasushi Totoki, Akihiko Yoshida, Momoko Nagai, Mamoru Kato, Erika Arakawa, Wakako Mukai, Hirofumi Rokutan, Akira Kawai, Sakae Tanaka, Tatsuhiro Shibata
Format: Article
Language:English
Published: Nature Portfolio 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03891-9

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