Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023

Vitamin C has multiple metabolic functions in the body, but the available information on the exact relationship between these functions and the intake necessary to maintain them is very limited. However, most attempts to objectively measure adequacy of vitamin C status, including, for example, repla...

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Main Authors: Jens Lykkesfeldt, Anitra C. Carr
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2023-12-01
Series:Food & Nutrition Research
Subjects:
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/10300/16661
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author Jens Lykkesfeldt
Anitra C. Carr
author_facet Jens Lykkesfeldt
Anitra C. Carr
author_sort Jens Lykkesfeldt
collection DOAJ
description Vitamin C has multiple metabolic functions in the body, but the available information on the exact relationship between these functions and the intake necessary to maintain them is very limited. However, most attempts to objectively measure adequacy of vitamin C status, including, for example, replacement of metabolic turnover, chronic disease prevention, urinary excretion, and saturation of immune cells and body compartment, currently point toward 50 µmol/L as a reasonable target plasma concentration. As a strong correlation between body weight and vitamin C status exists, recommended intakes (RIs) for other age groups may be extrapolated from the adult RI based on weight. However, as body weights above 70 kg are becoming increasingly common – also in the Nordic region – an RI of 140 mg/day for individuals weighing 100 kg or more should be considered to compensate for the larger volume of distribution. Finally, smoking continues to be a common contributor to poor vitamin C status; therefore, it is proposed that people who smoke increase their daily vitamin C intake by 40 mg/day to compensate for the increased metabolic turnover induced by smoking.
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spelling doaj.art-f39d4c2f49be43bdbcd15bf23e567f1f2024-01-05T15:01:05ZengSwedish Nutrition FoundationFood & Nutrition Research1654-661X2023-12-016711910.29219/fnr.v67.1030010300Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023Jens Lykkesfeldt0Anitra C. Carr1Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkDepartment of Pathology and Biomedical Science, University of Otago, Christchurch, New ZealandVitamin C has multiple metabolic functions in the body, but the available information on the exact relationship between these functions and the intake necessary to maintain them is very limited. However, most attempts to objectively measure adequacy of vitamin C status, including, for example, replacement of metabolic turnover, chronic disease prevention, urinary excretion, and saturation of immune cells and body compartment, currently point toward 50 µmol/L as a reasonable target plasma concentration. As a strong correlation between body weight and vitamin C status exists, recommended intakes (RIs) for other age groups may be extrapolated from the adult RI based on weight. However, as body weights above 70 kg are becoming increasingly common – also in the Nordic region – an RI of 140 mg/day for individuals weighing 100 kg or more should be considered to compensate for the larger volume of distribution. Finally, smoking continues to be a common contributor to poor vitamin C status; therefore, it is proposed that people who smoke increase their daily vitamin C intake by 40 mg/day to compensate for the increased metabolic turnover induced by smoking.https://foodandnutritionresearch.net/index.php/fnr/article/view/10300/16661vitamin cascorbic acidantioxidantsnutrition recommendations
spellingShingle Jens Lykkesfeldt
Anitra C. Carr
Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
Food & Nutrition Research
vitamin c
ascorbic acid
antioxidants
nutrition recommendations
title Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
title_full Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
title_fullStr Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
title_full_unstemmed Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
title_short Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
title_sort vitamin c a scoping review for nordic nutrition recommendations 2023
topic vitamin c
ascorbic acid
antioxidants
nutrition recommendations
url https://foodandnutritionresearch.net/index.php/fnr/article/view/10300/16661
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