Genetic Interaction of <i>Thm2</i> and <i>Thm1</i> Shapes Postnatal Craniofacial Bone

Genetic Interaction of <i>Thm2</i> and <i>Thm1</i> Shapes Postnatal Craniofacial Bone

Ciliopathies are genetic syndromes that link skeletal dysplasias to the dysfunction of primary cilia. Primary cilia are sensory organelles synthesized by intraflagellar transport (IFT)—A and B complexes, which traffic protein cargo along a microtubular core. We have reported that the deletion of the...

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Bibliographic Details
Main Authors: Erin E. Bumann, Portia Hahn Leat, Henry H. Wang, Brittany M. Hufft-Martinez, Wei Wang, Pamela V. Tran
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Developmental Biology
Subjects:
<i>Ttc21a</i>
<i>Ttc21b</i>
mouse knock-out
jaw
facial bone
viscerocranium
Online Access:https://www.mdpi.com/2221-3759/10/2/17

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