Long Non-Coding RNAs H19 and HOTAIR Implicated in Intervertebral Disc Degeneration

Long Non-Coding RNAs H19 and HOTAIR Implicated in Intervertebral Disc Degeneration

Objective: Intervertebral disc degeneration (IDD) is the major cause of low back pain. We aimed to identify the key genes for IDD pathogenesis.Methods: An integrated analysis of microarray datasets of IDD archived in public Gene Expression Omnibus was performed. Bioinformatics analyses including ide...

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Bibliographic Details
Main Authors: Zhun Wang, Jingwei Zhang, Wei Zheng, Yongjin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Genetics
Subjects:
H19
HOTAIR
differentially expressed genes
JAK–STAT pathway
intervertebral disc degeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.843599/full

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