A Liquid Chromatography-Mass Spectrometry Method to Study the Interaction between Membrane Proteins and Low-Molecular-Weight Compound Mixtures

A Liquid Chromatography-Mass Spectrometry Method to Study the Interaction between Membrane Proteins and Low-Molecular-Weight Compound Mixtures

Molecular interaction analysis is an essential technique for the study of biomolecular functions and the development of new drugs. Most current methods generally require manipulation to immobilize or label molecules, and require advance identification of at least one of the two molecules in the reac...

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Bibliographic Details
Main Authors: Hideo Ogiso, Ryoji Suno, Takuya Kobayashi, Masashi Kawami, Mikihisa Takano, Masaru Ogasawara
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
molecular interaction
high-resolution mass spectrometry
size-exclusion chromatography
membrane protein
ligand-receptor complex
GPCR
Online Access:https://www.mdpi.com/1420-3049/27/15/4889

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https://www.mdpi.com/1420-3049/27/15/4889

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