Lack of pharmacokinetic interaction between derazantinib and naringin in rats

Lack of pharmacokinetic interaction between derazantinib and naringin in rats

AbstractContext Derazantinib—an orally bioavailable, ATP competitive, multikinase inhibitor—has strong activity against fibroblast growth factor receptors (FGFR)2, FGFR1, and FGFR3 kinases. It has preliminary antitumor activity in patients with unresectable or metastatic FGFR2 fusion-positive intrah...

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Bibliographic Details
Main Authors:	Ya-nan Liu, Jie Chen, Xinhao Xu, Yingying Hu, Jin-yu Hu, Ren-ai Xu, Guanyang Lin
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Series:	Pharmaceutical Biology
Subjects:	Intrahepatic cholangiocarcinoma dose adjustment pharmacokinetics UPLC-MS/MS
Online Access:	https://www.tandfonline.com/doi/10.1080/13880209.2023.2185641

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