Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.

Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.

JC virus, JCV, is a human neurotropic polyomavirus whose replication in glial cells causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML). In addition, JCV possesses oncogenic activity and expression of its transforming protein, large T-antigen (T-Ag), in several ex...

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Bibliographic Details
Main Authors: Ilker Kudret Sariyer, Nana Merabova, Prem Kumer Patel, Tijana Knezevic, Alessandra Rosati, Maria C Turco, Kamel Khalili
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3440322?pdf=render

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