Colistin Resistance Gene mcr-1 Mediates Cell Permeability and Resistance to Hydrophobic Antibiotics

Colistin Resistance Gene mcr-1 Mediates Cell Permeability and Resistance to Hydrophobic Antibiotics

Colistin is considered the last-resort antibiotic used to treat multidrug resistant bacteria-related infections. However, the discovery of the plasmid-mediated colistin resistance gene, mcr-1, threatens the clinical utility of colistin antibiotics. In this study, the physiological function of MCR-1,...

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Bibliographic Details
Main Authors: Baiyuan Li, Fang Yin, Xuanyu Zhao, Yunxue Guo, Weiquan Wang, Pengxia Wang, Honghui Zhu, Yeshi Yin, Xiaoxue Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
mcr-1
colistin resistance
permeability
hydrophobic antibiotics
plasmid
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.03015/full

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