Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy

X-ray diffraction microscopy (XDM) is an established lens-less imaging method extensively practiced at synchrotrons and X-ray free-electron lasers (XFELs). XDM is broadly operated in two different modes: scanning and non-scanning. The non-scanning mode of operation in XDM is commonly called coherent...

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Main Authors: Katarzyna Kunio, Shirly Espinoza, Krishna P. Khakurel
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/9/12/934
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author Katarzyna Kunio
Shirly Espinoza
Krishna P. Khakurel
author_facet Katarzyna Kunio
Shirly Espinoza
Krishna P. Khakurel
author_sort Katarzyna Kunio
collection DOAJ
description X-ray diffraction microscopy (XDM) is an established lens-less imaging method extensively practiced at synchrotrons and X-ray free-electron lasers (XFELs). XDM is broadly operated in two different modes: scanning and non-scanning. The non-scanning mode of operation in XDM is commonly called coherent diffraction imaging (CDI) and has been the key research direction of many XFEL facilities. This method typically images objects smaller than the size of the illumination, which precludes the imaging of a large group of samples physically larger than the illumination. Furthermore, satisfying this requirement at X-ray free-electron lasers tremendously reduces the volume of practically useful data, leading the experimental scheme to be less efficient. Such a limitation can be circumvented by using a uniform illumination probe rather than the traditional Gaussian-focused probe from the X-ray focusing optics. Here in this article, we report a numerical study on the design of an optical element to generate uniform X-ray illumination and its application to the CDI. We demonstrate the benefits of such illumination in imaging objects that are larger than the illumination size and in improving the efficiency of the experimental scheme overall.
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spelling doaj.art-f3abf85973fe435b8958316694058d172023-11-24T17:25:01ZengMDPI AGPhotonics2304-67322022-12-0191293410.3390/photonics9120934Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction MicroscopyKatarzyna Kunio0Shirly Espinoza1Krishna P. Khakurel2Faculty of Electronics, Photonics and Microsystems, Wrocław University of Science and Technology, Wybrzeże Stanisława Wyspiańskiego 27, 50-370 Wrocław, PolandInstitute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 1999/2, 18221 Prague, Czech RepublicInstitute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 1999/2, 18221 Prague, Czech RepublicX-ray diffraction microscopy (XDM) is an established lens-less imaging method extensively practiced at synchrotrons and X-ray free-electron lasers (XFELs). XDM is broadly operated in two different modes: scanning and non-scanning. The non-scanning mode of operation in XDM is commonly called coherent diffraction imaging (CDI) and has been the key research direction of many XFEL facilities. This method typically images objects smaller than the size of the illumination, which precludes the imaging of a large group of samples physically larger than the illumination. Furthermore, satisfying this requirement at X-ray free-electron lasers tremendously reduces the volume of practically useful data, leading the experimental scheme to be less efficient. Such a limitation can be circumvented by using a uniform illumination probe rather than the traditional Gaussian-focused probe from the X-ray focusing optics. Here in this article, we report a numerical study on the design of an optical element to generate uniform X-ray illumination and its application to the CDI. We demonstrate the benefits of such illumination in imaging objects that are larger than the illumination size and in improving the efficiency of the experimental scheme overall.https://www.mdpi.com/2304-6732/9/12/934X-ray microscopyflat-top X-ray beamsX-ray free-electron lasers
spellingShingle Katarzyna Kunio
Shirly Espinoza
Krishna P. Khakurel
Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
Photonics
X-ray microscopy
flat-top X-ray beams
X-ray free-electron lasers
title Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
title_full Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
title_fullStr Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
title_full_unstemmed Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
title_short Generation of Uniform X-ray Illumination and Its Application to X-ray Diffraction Microscopy
title_sort generation of uniform x ray illumination and its application to x ray diffraction microscopy
topic X-ray microscopy
flat-top X-ray beams
X-ray free-electron lasers
url https://www.mdpi.com/2304-6732/9/12/934
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