Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature
Introduction: Primary spondylodiscitis due to Listeria monocytogenes (LM) is a rare condition. Research question: We present a case of spontaneous LM spondylodiscitis with an epidural abscess in a middle-aged man, who reported no gastrointestinal infection. Material and methods: We identified 5 spin...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Brain and Spine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529422008372 |
| _version_ | 1797977714098962432 |
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| author | Artur Vetkas Piret Mitt Reet Tikk |
| author_facet | Artur Vetkas Piret Mitt Reet Tikk |
| author_sort | Artur Vetkas |
| collection | DOAJ |
| description | Introduction: Primary spondylodiscitis due to Listeria monocytogenes (LM) is a rare condition. Research question: We present a case of spontaneous LM spondylodiscitis with an epidural abscess in a middle-aged man, who reported no gastrointestinal infection. Material and methods: We identified 5 spinal infection cases due to LM in the literature, with 3 diagnosed as primary spondylodiscitis. Results: The patient was treated with surgical decompression, debridement, and antibiotic therapy. Blood cultures remained negative throughout the case and microbiological cultures were obtained during surgery. The patient developed side-effects of prolonged gentamicin therapy but made a recovery from his spinal complaints at 6-months follow-up. Listeriosis is a relatively rare food-borne disease with a wide spectrum of presentation. Surgeons should consider more aggressive therapy for spinal infections and recognize the uncommon manifestations. We identified 3 primary and 2 secondary LM spondylodiscitis cases in the literature. Antibacterial treatment of LM spondylodiscitis varied in agents and duration, but no side-effects were previously reported. Gentamicin treatment requires care and attention to complications. Discussion and conclusion: Listeria monocytogenes is a rare cause of primary spondylodiscitis. Further studies are needed to establish a safe treatment protocol for treatment with gentamicin and LM spondylodiscitis. |
| first_indexed | 2024-04-11T05:12:28Z |
| format | Article |
| id | doaj.art-f3ac8fbef046401281e18023f5d9f96b |
| institution | Directory Open Access Journal |
| issn | 2772-5294 |
| language | English |
| last_indexed | 2024-04-11T05:12:28Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain and Spine |
| spelling | doaj.art-f3ac8fbef046401281e18023f5d9f96b2022-12-25T04:20:54ZengElsevierBrain and Spine2772-52942022-01-012101696Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literatureArtur Vetkas0Piret Mitt1Reet Tikk2Tartu University Hospital, Tartu, Estonia; Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Estonia; Corresponding author. Tartu University Hospital, 8 L. Puusepa St, Tartu, 50406, Estonia.Tartu University Hospital, Tartu, Estonia; Tartu University, Tartu, EstoniaTartu University Hospital, Tartu, Estonia; Tartu University, Tartu, EstoniaIntroduction: Primary spondylodiscitis due to Listeria monocytogenes (LM) is a rare condition. Research question: We present a case of spontaneous LM spondylodiscitis with an epidural abscess in a middle-aged man, who reported no gastrointestinal infection. Material and methods: We identified 5 spinal infection cases due to LM in the literature, with 3 diagnosed as primary spondylodiscitis. Results: The patient was treated with surgical decompression, debridement, and antibiotic therapy. Blood cultures remained negative throughout the case and microbiological cultures were obtained during surgery. The patient developed side-effects of prolonged gentamicin therapy but made a recovery from his spinal complaints at 6-months follow-up. Listeriosis is a relatively rare food-borne disease with a wide spectrum of presentation. Surgeons should consider more aggressive therapy for spinal infections and recognize the uncommon manifestations. We identified 3 primary and 2 secondary LM spondylodiscitis cases in the literature. Antibacterial treatment of LM spondylodiscitis varied in agents and duration, but no side-effects were previously reported. Gentamicin treatment requires care and attention to complications. Discussion and conclusion: Listeria monocytogenes is a rare cause of primary spondylodiscitis. Further studies are needed to establish a safe treatment protocol for treatment with gentamicin and LM spondylodiscitis.http://www.sciencedirect.com/science/article/pii/S2772529422008372SpondylodiscitisEpidural abscessSpine infectionVertebral osteomyelitisListeria monocytogenesGentamicin |
| spellingShingle | Artur Vetkas Piret Mitt Reet Tikk Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature Brain and Spine Spondylodiscitis Epidural abscess Spine infection Vertebral osteomyelitis Listeria monocytogenes Gentamicin |
| title | Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature |
| title_full | Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature |
| title_fullStr | Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature |
| title_full_unstemmed | Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature |
| title_short | Spontaneous spondylodiscitis and epidural abscess due to Listeria monocytogenes in a middle-aged patient with gentamicin related side effects: A case report and a review of literature |
| title_sort | spontaneous spondylodiscitis and epidural abscess due to listeria monocytogenes in a middle aged patient with gentamicin related side effects a case report and a review of literature |
| topic | Spondylodiscitis Epidural abscess Spine infection Vertebral osteomyelitis Listeria monocytogenes Gentamicin |
| url | http://www.sciencedirect.com/science/article/pii/S2772529422008372 |
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