Influence of continuous renal replacement therapy on the plasma concentration of tigecycline in patients with septic shock: A prospective observational study

Influence of continuous renal replacement therapy on the plasma concentration of tigecycline in patients with septic shock: A prospective observational study

Objective: The influence of continuous renal replacement therapy (CRRT) on the steady-state plasma concentration of high-dose tigecycline was investigated in septic shock patients to provide references for drug dosing.Methods: In this prospective observational study, 17 septic shock patients present...

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Bibliographic Details
Main Authors:	Fang Huang, Wen-Xiang Cao, Yu-Ying Yan, Tian-Tian Mao, Xian-Wen Wang, Dan Huang, Yu-Shuang Qiu, Wen-Jie Lu, Dong-Jie Li, Yu-Gang Zhuang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Pharmacology
Subjects:	high-dose tigecycline continuous renal replacement therapy septic shock plasma concentration dose adjustment
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1118788/full

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