<it>Abiotrophia defectiva </it>knee prosthesis infection: A case report
<p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>species have rarely been implicated in osteoarticular infections. We report one case of an <it>A. defectiva </it>knee prosthesis infection.</p> <p>Case presentation</p> &...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2011-09-01
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| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/5/1/438 |
| _version_ | 1828747100898197504 |
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| author | Levy Pierre-Yves Drancourt Michel Grillo Jean-Charles Argenson Jean-Noël Cassir Nadim |
| author_facet | Levy Pierre-Yves Drancourt Michel Grillo Jean-Charles Argenson Jean-Noël Cassir Nadim |
| author_sort | Levy Pierre-Yves |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>species have rarely been implicated in osteoarticular infections. We report one case of an <it>A. defectiva </it>knee prosthesis infection.</p> <p>Case presentation</p> <p>A 71-year-old man of Italian origin presented with pain and swelling of the knee four years after the implantation of a total knee replacement prosthesis. While standard culturing of the synovial fluid resulted in no isolation of microorganisms, the direct inoculation of the synovial fluid into a rich culture medium resulted in the identification of <it>A. defectiva </it>by polymerase chain reaction sequencing. Repeated attempts of culturing microorganisms from blood were negative, and echocardiograms and colonoscopies were unremarkable. High-dose amoxicillin for nine months and a two-stage replacement of the knee prosthesis led to full patient recovery by the time of the 12-month follow-up examination.</p> <p>Conclusions</p> <p>Because <it>Abiotrophia </it>spp. are fastidious microorganisms, it is likely that cases of <it>Abiotrophia </it>orthopedic infection are misdiagnosed as culture-negative infections. Direct inoculation of synovial fluids into rich broth medium and further polymerase chain reaction-based detection of culture-negative synovial fluids are key tests for accurate documentation and detection of these infections.</p> |
| first_indexed | 2024-04-14T04:36:37Z |
| format | Article |
| id | doaj.art-f3ae1c7dc1654f14bfe3211371d4aa5e |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-14T04:36:37Z |
| publishDate | 2011-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-f3ae1c7dc1654f14bfe3211371d4aa5e2022-12-22T02:11:51ZengBMCJournal of Medical Case Reports1752-19472011-09-015143810.1186/1752-1947-5-438<it>Abiotrophia defectiva </it>knee prosthesis infection: A case reportLevy Pierre-YvesDrancourt MichelGrillo Jean-CharlesArgenson Jean-NoëlCassir Nadim<p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>species have rarely been implicated in osteoarticular infections. We report one case of an <it>A. defectiva </it>knee prosthesis infection.</p> <p>Case presentation</p> <p>A 71-year-old man of Italian origin presented with pain and swelling of the knee four years after the implantation of a total knee replacement prosthesis. While standard culturing of the synovial fluid resulted in no isolation of microorganisms, the direct inoculation of the synovial fluid into a rich culture medium resulted in the identification of <it>A. defectiva </it>by polymerase chain reaction sequencing. Repeated attempts of culturing microorganisms from blood were negative, and echocardiograms and colonoscopies were unremarkable. High-dose amoxicillin for nine months and a two-stage replacement of the knee prosthesis led to full patient recovery by the time of the 12-month follow-up examination.</p> <p>Conclusions</p> <p>Because <it>Abiotrophia </it>spp. are fastidious microorganisms, it is likely that cases of <it>Abiotrophia </it>orthopedic infection are misdiagnosed as culture-negative infections. Direct inoculation of synovial fluids into rich broth medium and further polymerase chain reaction-based detection of culture-negative synovial fluids are key tests for accurate documentation and detection of these infections.</p>http://www.jmedicalcasereports.com/content/5/1/438 |
| spellingShingle | Levy Pierre-Yves Drancourt Michel Grillo Jean-Charles Argenson Jean-Noël Cassir Nadim <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report Journal of Medical Case Reports |
| title | <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report |
| title_full | <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report |
| title_fullStr | <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report |
| title_full_unstemmed | <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report |
| title_short | <it>Abiotrophia defectiva </it>knee prosthesis infection: A case report |
| title_sort | it abiotrophia defectiva it knee prosthesis infection a case report |
| url | http://www.jmedicalcasereports.com/content/5/1/438 |
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