High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures

High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures

Abstract Background Excessive energy intake in modern society has led to an epidemic surge in metabolic diseases, such as obesity and type 2 diabetes, posing profound threats to women’s reproductive health. However, the precise impact and underlying pathogenesis of energy excess on female reproducti...

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Bibliographic Details
Main Authors: Congcong Liu, Yunde Dou, Mengge Zhang, Shan Han, Shourui Hu, Yuxuan Li, Zhiheng Yu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Han Zhao, Yuqing Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Female reproduction
High-fat and high-sucrose
Polycystic ovary syndrome
Metabolism
Online Access:https://doi.org/10.1186/s12967-024-04952-y

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