Cationic micelle-based siRNA delivery for efficient colon cancer gene therapy

Cationic micelle-based siRNA delivery for efficient colon cancer gene therapy

Abstract Small interfering RNA (siRNA)-based gene therapy has provided an alternative strategy for cancer therapy. One of the key components within gene therapy process is the delivery system. As a novel non-viral gene vector, DMP, prepared by modifying mPEG-PCL micelle with cationic DOTAP lipid, ha...

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Bibliographic Details
Main Authors: Yongping Lu, Lei Zhong, Zhongliang Jiang, Haixia Pan, Yuanfa Zhang, Guonian Zhu, Lan Bai, Rongsheng Tong, Jianyou Shi, Xingmei Duan
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:Nanoscale Research Letters
Subjects:
Non-viral vector
Gene therapy
Gene delivery
RNAi
siRNA
C26 colon cancer
Online Access:http://link.springer.com/article/10.1186/s11671-019-2985-z

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