Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol

Background: Beach chair position (BCP) is used in arthroscopic shoulder operations for its advantages. The BCP together with deliberate hypotension used to decrease intraoperative blood loss during arthroscopic shoulder procedures, this may have risk to cause postoperative neurological insults. Dexm...

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Main Authors: Khaled Mohammed Maghawry, Ashraf El Sayed El-Agamy, Wael Ibrahim Tahir, Ayman F. Zein
Format: Article
Language:English
Published: Taylor & Francis Group 2015-01-01
Series:Egyptian Journal of Anaesthesia
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110184914000865
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author Khaled Mohammed Maghawry
Ashraf El Sayed El-Agamy
Wael Ibrahim Tahir
Ayman F. Zein
author_facet Khaled Mohammed Maghawry
Ashraf El Sayed El-Agamy
Wael Ibrahim Tahir
Ayman F. Zein
author_sort Khaled Mohammed Maghawry
collection DOAJ
description Background: Beach chair position (BCP) is used in arthroscopic shoulder operations for its advantages. The BCP together with deliberate hypotension used to decrease intraoperative blood loss during arthroscopic shoulder procedures, this may have risk to cause postoperative neurological insults. Dexmedetomidine and esmolol are used to induce deliberate hypotension. Near-infrared spectroscopy (NIRS) provides a non-invasive technique of continuous monitoring of regional cerebral tissue oxygen saturation (rScO2). In this study we evaluate the prevalence of rScO2 during hypotensive anesthesia induced by intra-operative infusion of either dexmedetomidine or esmolol in patients undergoing elective arthroscopic shoulder surgery in the BCP. Patients and methods: Fifty patients scheduled for elective arthroscopic shoulder surgery under general anesthesia with hypotensive technique in BCP, randomly assigned into two equal groups, dexmedetomidine group (D Group) and esmolol group (E Group) according to the drug used for deliberate hypotension. MAP, HR, BIS and rScO2 were recorded before induction of anesthesia T0, post-induction of anesthesia T1 as baseline, 5 min after BCP T2, 5 min after starting the studied drug T3, 30 min T4, 60 min T5, 90 min T6, 5 min after stopping the studied drug T7, 5 min after return to supine T8 and after extubation T9. Results: In D group there was significant decrease in Lt.rsco2 and Rt.rsco2, at T2 to T7 compared to T1. In E group there was significant decrease in Lt.rsco2 and Rt.rsco2 at T2, to T7 compared to T1. In D group two patients had CDEs compared to five patients in E group. Conclusion: In patients undergoing shoulder arthroscopic surgery under general anesthesia, the BCP significantly decreases rScO2, with further slight decrease of rScO2 with dexmedetomidine and esmolol induced hypotension with no affection of postoperative cognitive function with both drugs. Dexmedetomidine and esmolol are safe drugs with better safety of dexmedetomidine over esmolol.
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spelling doaj.art-f3b13f3d9f9b415b9eaab43e48b5356a2022-12-21T23:54:28ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492015-01-01311435210.1016/j.egja.2014.09.003Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmololKhaled Mohammed Maghawry0Ashraf El Sayed El-Agamy1Wael Ibrahim Tahir2Ayman F. Zein3Department of Anesthesiology, Faculty of Medicine, Ain Shams University, Cairo, EgyptDepartment of Anesthesiology, Faculty of Medicine, Ain Shams University, Cairo, EgyptDepartment of Anesthesiology, Faculty of Medicine, Ain Shams University, Cairo, EgyptOrthopedic Department, Prince Salman Hospital, Saudi ArabiaBackground: Beach chair position (BCP) is used in arthroscopic shoulder operations for its advantages. The BCP together with deliberate hypotension used to decrease intraoperative blood loss during arthroscopic shoulder procedures, this may have risk to cause postoperative neurological insults. Dexmedetomidine and esmolol are used to induce deliberate hypotension. Near-infrared spectroscopy (NIRS) provides a non-invasive technique of continuous monitoring of regional cerebral tissue oxygen saturation (rScO2). In this study we evaluate the prevalence of rScO2 during hypotensive anesthesia induced by intra-operative infusion of either dexmedetomidine or esmolol in patients undergoing elective arthroscopic shoulder surgery in the BCP. Patients and methods: Fifty patients scheduled for elective arthroscopic shoulder surgery under general anesthesia with hypotensive technique in BCP, randomly assigned into two equal groups, dexmedetomidine group (D Group) and esmolol group (E Group) according to the drug used for deliberate hypotension. MAP, HR, BIS and rScO2 were recorded before induction of anesthesia T0, post-induction of anesthesia T1 as baseline, 5 min after BCP T2, 5 min after starting the studied drug T3, 30 min T4, 60 min T5, 90 min T6, 5 min after stopping the studied drug T7, 5 min after return to supine T8 and after extubation T9. Results: In D group there was significant decrease in Lt.rsco2 and Rt.rsco2, at T2 to T7 compared to T1. In E group there was significant decrease in Lt.rsco2 and Rt.rsco2 at T2, to T7 compared to T1. In D group two patients had CDEs compared to five patients in E group. Conclusion: In patients undergoing shoulder arthroscopic surgery under general anesthesia, the BCP significantly decreases rScO2, with further slight decrease of rScO2 with dexmedetomidine and esmolol induced hypotension with no affection of postoperative cognitive function with both drugs. Dexmedetomidine and esmolol are safe drugs with better safety of dexmedetomidine over esmolol.http://www.sciencedirect.com/science/article/pii/S1110184914000865Cerebral oximetryHypotensive anesthesiaArthroscopyDexmedetomidineEsmolol
spellingShingle Khaled Mohammed Maghawry
Ashraf El Sayed El-Agamy
Wael Ibrahim Tahir
Ayman F. Zein
Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
Egyptian Journal of Anaesthesia
Cerebral oximetry
Hypotensive anesthesia
Arthroscopy
Dexmedetomidine
Esmolol
title Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
title_full Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
title_fullStr Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
title_full_unstemmed Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
title_short Cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy: A comparative study between dexmedetomidine and esmolol
title_sort cerebral oxygen saturation monitoring during hypotensive anesthesia in shoulder arthroscopy a comparative study between dexmedetomidine and esmolol
topic Cerebral oximetry
Hypotensive anesthesia
Arthroscopy
Dexmedetomidine
Esmolol
url http://www.sciencedirect.com/science/article/pii/S1110184914000865
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