Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives

Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives

Abstract N-acylhydrazones are considered privileged structures in medicinal chemistry, being part of antimicrobial compounds (for example). In this study we show the activity of N-acylhydrazone compounds, namely AH1, AH2, AH4, AH5 in in vitro tests against the chloroquine-resistant strain of Plasmod...

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Main Authors: Fernanda A. Oliveira, Ana Claudia S. Pinto, Caique L. Duarte, Alex G. Taranto, Eder Lorenzato Junior, Cleydson Finotti Cordeiro, Diogo T. Carvalho, Fernando P. Varotti, Amanda L. Fonseca
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Chemistry
Subjects:
Malaria
Bioinformatics
Molecular modeling
Online Access:https://doi.org/10.1186/s13065-022-00843-9

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