Association between altered metabolism and genetic mutations in human glioma

Abstract Background Molecular markers for classification of gliomas include isocitrate dehydrogenase (IDH) mutations and codeletion of chromosomal arms 1p and 19q (1p/19q). While mutations in IDH enzymes result in the well‐characterized production of oncometabolite 2‐hydroxyglutarate, dysregulation...

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Bibliographic Details
Main Authors: Hannah Pearl, Candace C. Fleischer
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1799