Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

Abstract Background Elevated transforming growth factor (TGF)-β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma (POAG), but TGF-β2 is downregulated in secondary open-angle glaucoma (...

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Bibliographic Details
Main Authors: Nozomi Igarashi, Megumi Honjo, Reiko Yamagishi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Toshikatsu Kaburaki, Makoto Aihara
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Biomedical Science
Subjects:
Transforming Growth factor β
Autotaxin
Glaucoma
Human trabecular meshwork
Online Access:https://doi.org/10.1186/s12929-021-00745-3

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