Insight into the Evolving Role of PCSK9

Insight into the Evolving Role of PCSK9

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is the last discovered member of the family of proprotein convertases (PCs), mainly synthetized in hepatic cells. This serine protease plays a pivotal role in the reduction of the number of low-density lipoprotein receptors (LDLRs) on the surface...

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Bibliographic Details
Main Authors: Mateusz Maligłówka, Michał Kosowski, Marcin Hachuła, Marcin Cyrnek, Łukasz Bułdak, Marcin Basiak, Aleksandra Bołdys, Grzegorz Machnik, Rafał Jakub Bułdak, Bogusław Okopień
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Metabolites
Subjects:
PCSK9
cholesterol
anti-PCSK9
cardiovascular diseases
genetic
atherosclerosis
Online Access:https://www.mdpi.com/2218-1989/12/3/256

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