| Summary: | Michael addition–halogenation–intramolecular ring-closing (MHIRC) reactions are processes in which a halogen atom as a leaving group can attach to substrates or reactants during the reaction, which then undergoes intramolecular ring closure. In this communication the MHIRC transformation of 4-benzylidene-3-phenylisoxazol-5(4<i>H</i>)-one and 1,3-dimethylbarbituric acid in the presence of <i>N</i>-bromosuccinimide and sodium acetate in EtOH at room temperature was carefully investigated to give novel 1,3-dimethyl-3′,5-diphenyl-1,5-dihydro-2<i>H</i>,5′<i>H</i>-spiro[furo[2,3-<i>d</i>]pyrimi- dine-6,4′-isoxazole]-2,4,5′(3<i>H</i>)-trione in a good yield. The structure of the new compound was confirmed by the results of elemental analysis as well as mass, nuclear magnetic resonance, and infrared spectroscopy.
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