The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-04691-8 |
_version_ | 1797853689123176448 |
---|---|
author | Shunsuke Takeuchi Kimiko Shimizu Yoshitaka Fukada Kazuo Emoto |
author_facet | Shunsuke Takeuchi Kimiko Shimizu Yoshitaka Fukada Kazuo Emoto |
author_sort | Shunsuke Takeuchi |
collection | DOAJ |
description | Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission. |
first_indexed | 2024-04-09T19:53:41Z |
format | Article |
id | doaj.art-f3bf1db0122c494f952f47ac6a051078 |
institution | Directory Open Access Journal |
issn | 2399-3642 |
language | English |
last_indexed | 2024-04-09T19:53:41Z |
publishDate | 2023-03-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Communications Biology |
spelling | doaj.art-f3bf1db0122c494f952f47ac6a0510782023-04-03T05:36:25ZengNature PortfolioCommunications Biology2399-36422023-03-016111210.1038/s42003-023-04691-8The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activityShunsuke Takeuchi0Kimiko Shimizu1Yoshitaka Fukada2Kazuo Emoto3Department of Biological Sciences, Graduate School of Science, The University of TokyoDepartment of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental UniversityDepartment of Biological Sciences, Graduate School of Science, The University of TokyoDepartment of Biological Sciences, Graduate School of Science, The University of TokyoLoss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.https://doi.org/10.1038/s42003-023-04691-8 |
spellingShingle | Shunsuke Takeuchi Kimiko Shimizu Yoshitaka Fukada Kazuo Emoto The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity Communications Biology |
title | The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity |
title_full | The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity |
title_fullStr | The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity |
title_full_unstemmed | The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity |
title_short | The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity |
title_sort | circadian clock in the piriform cortex intrinsically tunes daily changes of odor evoked neural activity |
url | https://doi.org/10.1038/s42003-023-04691-8 |
work_keys_str_mv | AT shunsuketakeuchi thecircadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT kimikoshimizu thecircadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT yoshitakafukada thecircadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT kazuoemoto thecircadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT shunsuketakeuchi circadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT kimikoshimizu circadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT yoshitakafukada circadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity AT kazuoemoto circadianclockinthepiriformcortexintrinsicallytunesdailychangesofodorevokedneuralactivity |