The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity

Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.

Bibliographic Details
Main Authors: Shunsuke Takeuchi, Kimiko Shimizu, Yoshitaka Fukada, Kazuo Emoto
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04691-8
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author Shunsuke Takeuchi
Kimiko Shimizu
Yoshitaka Fukada
Kazuo Emoto
author_facet Shunsuke Takeuchi
Kimiko Shimizu
Yoshitaka Fukada
Kazuo Emoto
author_sort Shunsuke Takeuchi
collection DOAJ
description Loss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.
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spelling doaj.art-f3bf1db0122c494f952f47ac6a0510782023-04-03T05:36:25ZengNature PortfolioCommunications Biology2399-36422023-03-016111210.1038/s42003-023-04691-8The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activityShunsuke Takeuchi0Kimiko Shimizu1Yoshitaka Fukada2Kazuo Emoto3Department of Biological Sciences, Graduate School of Science, The University of TokyoDepartment of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental UniversityDepartment of Biological Sciences, Graduate School of Science, The University of TokyoDepartment of Biological Sciences, Graduate School of Science, The University of TokyoLoss of the clock gene, Bmal1, in the piriform cortex largely abolishes the circadian rhythm of odor-evoked activity in mice, suggesting a broader regulatory role for Bmal1 in olfactory neural activity and transmission.https://doi.org/10.1038/s42003-023-04691-8
spellingShingle Shunsuke Takeuchi
Kimiko Shimizu
Yoshitaka Fukada
Kazuo Emoto
The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
Communications Biology
title The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
title_full The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
title_fullStr The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
title_full_unstemmed The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
title_short The circadian clock in the piriform cortex intrinsically tunes daily changes of odor-evoked neural activity
title_sort circadian clock in the piriform cortex intrinsically tunes daily changes of odor evoked neural activity
url https://doi.org/10.1038/s42003-023-04691-8
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