Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey

Background: As vaccination against coronavirus disase-19 (COVID-19) evolves, hesitancy has become a problematic issue that has gradually spread worldwide. The main reason for vaccine hesitancy is uncertainties about vaccine side effects. Aims: To evaluate the safety of an inactivated COVID-19 vacci...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Oya Baydar, Şennur Özen, Burcu Öztürk Şahin, Nurdan Köktürk, Mehmet Tevfik Kitapçı
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Galenos Publishing House 2022-05-01
Ráidu:Balkan Medical Journal
Liŋkkat:http://www.balkanmedicaljournal.org/abstract.php?lang=en&id=2394
_version_ 1828018206155997184
author Oya Baydar
Şennur Özen
Burcu Öztürk Şahin
Nurdan Köktürk
Mehmet Tevfik Kitapçı
author_facet Oya Baydar
Şennur Özen
Burcu Öztürk Şahin
Nurdan Köktürk
Mehmet Tevfik Kitapçı
author_sort Oya Baydar
collection DOAJ
description Background: As vaccination against coronavirus disase-19 (COVID-19) evolves, hesitancy has become a problematic issue that has gradually spread worldwide. The main reason for vaccine hesitancy is uncertainties about vaccine side effects. Aims: To evaluate the safety of an inactivated COVID-19 vaccine, CoronaVac, and determine the risk factors of emergence of side effects. Study Design: Cross-sectional study. Methods: An online questionnaire was administered via the internet to healthcare workers who received one or two doses of CoronaVac. The online survey consisted of three sections detailing sociodemographic data, COVID-19 history, and post-vaccine side effects. Side effects that occurred in the period starting from immediately after the first vaccination to the end of the 14th day after the second vaccination were recorded. Results: A total of 1628 healthcare workers responded to the online survey. Of these, 24.3% had a side effect either after the first or second dose of CoronaVac. Redness and/or pain at the inoculation site, headache, muscle and joint pains, palpitations, and dizziness were the most common side effects. Female sex, age <50 years, and thyroid disorder in the pre-vaccine period were found to be risk factors for the emergence of side effects. Blood pressure control could not be achieved in 2.2% of participants despite medication use, and permanent medication was needed in 2.5% of participants for blood pressure control. Conclusion: Almost a quarter of healthcare workers have at least one side effect after the first or second dose of CoronaVac. Female gender, age <50 years, and thyroid disorder appear to be risk factors for the occurrence of side effects.
first_indexed 2024-04-10T11:00:30Z
format Article
id doaj.art-f3c10d1528a846dca22f67c4d4707c63
institution Directory Open Access Journal
issn 2146-3123
2146-3131
language English
last_indexed 2024-04-10T11:00:30Z
publishDate 2022-05-01
publisher Galenos Publishing House
record_format Article
series Balkan Medical Journal
spelling doaj.art-f3c10d1528a846dca22f67c4d4707c632023-02-15T16:19:45ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312022-05-0139319319810.4274/balkanmedj.galenos.2022.2021-11-25Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online SurveyOya Baydar0https://orcid.org/0000-0001-7320-976XŞennur Özen1https://orcid.org/0000-0002-2061-7046Burcu Öztürk Şahin2https://orcid.org/0000-0001-6444-4127Nurdan Köktürk3https://orcid.org/0000-0002-2889-7265Mehmet Tevfik Kitapçı4https://orcid.org/0000-0003-3543-7707Department of Chest Diseases, Faculty of Medicine Çukurova University, Adana, TurkeyClinic of Chest Diseaases, Delta Hospital, İstanbul, TurkeyDepartment of Chest Diseases Faculty of Medicine Gazi University, Ankara, TurkeyDepartment of Chest Diseases Faculty of Medicine Gazi University, Ankara, TurkeyDepartment of Nuclear medicine, Integra Medical Center, Ankara, TurkeyBackground: As vaccination against coronavirus disase-19 (COVID-19) evolves, hesitancy has become a problematic issue that has gradually spread worldwide. The main reason for vaccine hesitancy is uncertainties about vaccine side effects. Aims: To evaluate the safety of an inactivated COVID-19 vaccine, CoronaVac, and determine the risk factors of emergence of side effects. Study Design: Cross-sectional study. Methods: An online questionnaire was administered via the internet to healthcare workers who received one or two doses of CoronaVac. The online survey consisted of three sections detailing sociodemographic data, COVID-19 history, and post-vaccine side effects. Side effects that occurred in the period starting from immediately after the first vaccination to the end of the 14th day after the second vaccination were recorded. Results: A total of 1628 healthcare workers responded to the online survey. Of these, 24.3% had a side effect either after the first or second dose of CoronaVac. Redness and/or pain at the inoculation site, headache, muscle and joint pains, palpitations, and dizziness were the most common side effects. Female sex, age <50 years, and thyroid disorder in the pre-vaccine period were found to be risk factors for the emergence of side effects. Blood pressure control could not be achieved in 2.2% of participants despite medication use, and permanent medication was needed in 2.5% of participants for blood pressure control. Conclusion: Almost a quarter of healthcare workers have at least one side effect after the first or second dose of CoronaVac. Female gender, age <50 years, and thyroid disorder appear to be risk factors for the occurrence of side effects.http://www.balkanmedicaljournal.org/abstract.php?lang=en&id=2394
spellingShingle Oya Baydar
Şennur Özen
Burcu Öztürk Şahin
Nurdan Köktürk
Mehmet Tevfik Kitapçı
Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
Balkan Medical Journal
title Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
title_full Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
title_fullStr Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
title_full_unstemmed Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
title_short Safety of an Inactivated SARS-CoV-2 Vaccine Among Healthcare Workers in Turkey: An Online Survey
title_sort safety of an inactivated sars cov 2 vaccine among healthcare workers in turkey an online survey
url http://www.balkanmedicaljournal.org/abstract.php?lang=en&id=2394
work_keys_str_mv AT oyabaydar safetyofaninactivatedsarscov2vaccineamonghealthcareworkersinturkeyanonlinesurvey
AT sennurozen safetyofaninactivatedsarscov2vaccineamonghealthcareworkersinturkeyanonlinesurvey
AT burcuozturksahin safetyofaninactivatedsarscov2vaccineamonghealthcareworkersinturkeyanonlinesurvey
AT nurdankokturk safetyofaninactivatedsarscov2vaccineamonghealthcareworkersinturkeyanonlinesurvey
AT mehmettevfikkitapcı safetyofaninactivatedsarscov2vaccineamonghealthcareworkersinturkeyanonlinesurvey