Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.

Fermentation of these macromolecular food or pharmaceutical excipient ingredients by the gut microbiota leads to the formation of short chain fatty acids (SCFA) which can be absorbed from the gut into the general circulation. Circulating SFCA activate downstream effectors responsible for energy and...

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Main Author: Shireesh Apte
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-09-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/920-macromolecular-excipients-exert-biological-effects-via-their-microbial-fermentation-absorbable-products
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author Shireesh Apte
author_facet Shireesh Apte
author_sort Shireesh Apte
collection DOAJ
description Fermentation of these macromolecular food or pharmaceutical excipient ingredients by the gut microbiota leads to the formation of short chain fatty acids (SCFA) which can be absorbed from the gut into the general circulation. Circulating SFCA activate downstream effectors responsible for energy and glucose intake and expenditure. Macromolecular excipients can hence exert biological effects via their microbial fermentation absorbable products.
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spelling doaj.art-f3c25e777ce94a219293370089d7842c2024-03-20T18:01:27ZengInternational Pharmaceutical Excipients CouncilJournal of Excipients and Food Chemicals2150-26682016-09-0171Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.Shireesh ApteFermentation of these macromolecular food or pharmaceutical excipient ingredients by the gut microbiota leads to the formation of short chain fatty acids (SCFA) which can be absorbed from the gut into the general circulation. Circulating SFCA activate downstream effectors responsible for energy and glucose intake and expenditure. Macromolecular excipients can hence exert biological effects via their microbial fermentation absorbable products.https://jefc.scholasticahq.com/article/920-macromolecular-excipients-exert-biological-effects-via-their-microbial-fermentation-absorbable-products
spellingShingle Shireesh Apte
Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
Journal of Excipients and Food Chemicals
title Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
title_full Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
title_fullStr Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
title_full_unstemmed Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
title_short Macromolecular excipients exert biological effects via their microbial fermentation absorbable products.
title_sort macromolecular excipients exert biological effects via their microbial fermentation absorbable products
url https://jefc.scholasticahq.com/article/920-macromolecular-excipients-exert-biological-effects-via-their-microbial-fermentation-absorbable-products
work_keys_str_mv AT shireeshapte macromolecularexcipientsexertbiologicaleffectsviatheirmicrobialfermentationabsorbableproducts