Antimicrobial Peptide Omiganan Enhances Interferon Responses to Endosomal Toll‐Like Receptor Ligands in Human Peripheral Blood Mononuclear Cells

LL‐37 is a cationic antimicrobial peptide and the sole human member of cathelicidins. Besides its bactericidal properties, LL‐37 is known to have direct immunomodulatory effects, among which enhancement of antiviral responses via endosomal toll‐like receptors (TLRs). Omiganan pentahydrochloride is a...

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Bibliographic Details
Main Authors: Hendrika W. Grievink, Silvana M. G. Jirka, Tess D. Woutman, Mascha Schoonakker, Robert Rissmann, Karen E. Malone, Gary Feiss, Matthijs Moerland
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12789