Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review

Respiratory diseases are one of the leading causes of death in the world, which is why a lot of attention has been recently paid to studying the possible mechanisms for the development of pulmonary diseases and assessing the impact on their course. The microbiota plays an important role in these pro...

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Main Authors: Angelika Krumina, Marina Bogdanova, Sandra Gintere, Ludmila Viksna
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/12/1760
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author Angelika Krumina
Marina Bogdanova
Sandra Gintere
Ludmila Viksna
author_facet Angelika Krumina
Marina Bogdanova
Sandra Gintere
Ludmila Viksna
author_sort Angelika Krumina
collection DOAJ
description Respiratory diseases are one of the leading causes of death in the world, which is why a lot of attention has been recently paid to studying the possible mechanisms for the development of pulmonary diseases and assessing the impact on their course. The microbiota plays an important role in these processes and influences the functionality of the human immune system. Thus, alterations in the normal microflora contribute to a reduction in immunity and a more severe course of diseases. In this review, we summarized the information about gut and lung microbiota interactions with particular attention to their influence on the course of chronic obstructive pulmonary disease (COPD).
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spelling doaj.art-f3c8750841b1433e81b962aa4f6cf90a2023-11-24T16:32:15ZengMDPI AGMedicina1010-660X1648-91442022-11-015812176010.3390/medicina58121760Gut–Lung Microbiota Interaction in COPD Patients: A Literature ReviewAngelika Krumina0Marina Bogdanova1Sandra Gintere2Ludmila Viksna3Department of Infectology, Riga Stradiņš University, 16 Dzirciema Street, LV-1007 Riga, LatviaFaculty of Residency, Riga Stradiņš University, 16 Dzirciema Street, LV-1007 Riga, LatviaDepartment of Family Medicine, Riga Stradiņš University, 16 Dzirciema Street, LV-1007 Riga, LatviaDepartment of Infectology, Riga Stradiņš University, 16 Dzirciema Street, LV-1007 Riga, LatviaRespiratory diseases are one of the leading causes of death in the world, which is why a lot of attention has been recently paid to studying the possible mechanisms for the development of pulmonary diseases and assessing the impact on their course. The microbiota plays an important role in these processes and influences the functionality of the human immune system. Thus, alterations in the normal microflora contribute to a reduction in immunity and a more severe course of diseases. In this review, we summarized the information about gut and lung microbiota interactions with particular attention to their influence on the course of chronic obstructive pulmonary disease (COPD).https://www.mdpi.com/1648-9144/58/12/1760COPDmicrobiotachronic obstructive lung diseasedysbiosislungimmunity
spellingShingle Angelika Krumina
Marina Bogdanova
Sandra Gintere
Ludmila Viksna
Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
Medicina
COPD
microbiota
chronic obstructive lung disease
dysbiosis
lung
immunity
title Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
title_full Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
title_fullStr Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
title_full_unstemmed Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
title_short Gut–Lung Microbiota Interaction in COPD Patients: A Literature Review
title_sort gut lung microbiota interaction in copd patients a literature review
topic COPD
microbiota
chronic obstructive lung disease
dysbiosis
lung
immunity
url https://www.mdpi.com/1648-9144/58/12/1760
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AT marinabogdanova gutlungmicrobiotainteractionincopdpatientsaliteraturereview
AT sandragintere gutlungmicrobiotainteractionincopdpatientsaliteraturereview
AT ludmilaviksna gutlungmicrobiotainteractionincopdpatientsaliteraturereview