Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017
Introduction: Pulmonary disease produced by nontuberculous mycobacteria and pulmonary tuberculosis can share clinical signs and symptoms. It is important to discern one from the other in order to provide the proper treatment and programmatic management. Objective: To describe the frequency of non...
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| Format: | Article |
| Language: | English |
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Universidad Libre
2021-06-01
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| Series: | Interdisciplinary Journal of Epidemiology and Public Health |
| Subjects: | |
| Online Access: | https://revistas.unilibre.edu.co/index.php/iJEPH/article/view/5449 |
| _version_ | 1797804232252850176 |
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| author | Luis Eduardo Delgado Daniela Rocío Escobar Diana Marcela Hoyos Lucy Luna Robinson Pacheco López Beatriz E. Ferro |
| author_facet | Luis Eduardo Delgado Daniela Rocío Escobar Diana Marcela Hoyos Lucy Luna Robinson Pacheco López Beatriz E. Ferro |
| author_sort | Luis Eduardo Delgado |
| collection | DOAJ |
| description | Introduction: Pulmonary disease produced by nontuberculous mycobacteria and pulmonary tuberculosis can share clinical signs and symptoms. It is important to discern one from the other in order to provide the proper treatment and programmatic management.
Objective: To describe the frequency of nontuberculous mycobacteria isolated from patients registered in the tuberculosis control program in Cali.
Methods: We conducted a descriptive study to know what extent of the pulmonary tuberculosis load in Cali-Colombia corresponds to nontuberculous mycobacteria, in a four-year period, 2014-2017. Demographic (sex, age, health insurance), clinical (diagnosis dates, laboratory data, comorbidities) and programmatic data (tuberculosis treatment initiation and duration) was collected for statistical analysis.
Results: Of 3,651 patients registered in the local tuberculosis program with an initial diagnosis of pulmonary tuberculosis, 2,904 had sputum culture and among them 1.5% (43/2904) had nontuberculous mycobacteria isolation rather than Mycobacterium tuberculosis. Most of the nontuberculous mycobacteria isolates were not identified at the species level; M. fortuitum and M. abscessus were the most common species identified. 86% of patients initiated unnecessary tuberculosis treatment.
Conclusion: Nontuberculous mycobacteria isolation from pulmonary samples could be frequent in patients registered in the tuberculosis program in Cali, Colombia. The lack of clinical suspicion, the limited laboratory infrastructure, and the absence of a reporting system could be contributing factors to underestimate the importance of nontuberculous mycobacteria in this setting. We recommend that nontuberculous mycobacteria identification should be considered for public health intervention. |
| first_indexed | 2024-03-13T05:33:04Z |
| format | Article |
| id | doaj.art-f3c8cf8284794263a9e0a8f78ef0d8fe |
| institution | Directory Open Access Journal |
| issn | 2665-427X |
| language | English |
| last_indexed | 2024-03-13T05:33:04Z |
| publishDate | 2021-06-01 |
| publisher | Universidad Libre |
| record_format | Article |
| series | Interdisciplinary Journal of Epidemiology and Public Health |
| spelling | doaj.art-f3c8cf8284794263a9e0a8f78ef0d8fe2023-06-14T15:11:55ZengUniversidad LibreInterdisciplinary Journal of Epidemiology and Public Health2665-427X2021-06-012110.18041/2665-427X/ijeph.1.54496778Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017Luis Eduardo Delgado0Daniela Rocío Escobar1Diana Marcela Hoyos2Lucy Luna3Robinson Pacheco López4Beatriz E. Ferro5https://orcid.org/0000-0001-6045-1610Facultad de Ciencias de la Salud, Universidad Icesi, Cali, ColombiaFacultad de Ciencias de la Salud, Universidad Icesi, Cali, ColombiaSecretaría Departamental de Salud Pública, Valle del Cauca, ColombiaSecretaria de Salud Pública Municipal de CaliFacultad de Ciencias de la Salud, Universidad Icesi, Cali, ColombiaFacultad de Ciencias de la Salud, Universidad Icesi, Cali, ColombiaIntroduction: Pulmonary disease produced by nontuberculous mycobacteria and pulmonary tuberculosis can share clinical signs and symptoms. It is important to discern one from the other in order to provide the proper treatment and programmatic management. Objective: To describe the frequency of nontuberculous mycobacteria isolated from patients registered in the tuberculosis control program in Cali. Methods: We conducted a descriptive study to know what extent of the pulmonary tuberculosis load in Cali-Colombia corresponds to nontuberculous mycobacteria, in a four-year period, 2014-2017. Demographic (sex, age, health insurance), clinical (diagnosis dates, laboratory data, comorbidities) and programmatic data (tuberculosis treatment initiation and duration) was collected for statistical analysis. Results: Of 3,651 patients registered in the local tuberculosis program with an initial diagnosis of pulmonary tuberculosis, 2,904 had sputum culture and among them 1.5% (43/2904) had nontuberculous mycobacteria isolation rather than Mycobacterium tuberculosis. Most of the nontuberculous mycobacteria isolates were not identified at the species level; M. fortuitum and M. abscessus were the most common species identified. 86% of patients initiated unnecessary tuberculosis treatment. Conclusion: Nontuberculous mycobacteria isolation from pulmonary samples could be frequent in patients registered in the tuberculosis program in Cali, Colombia. The lack of clinical suspicion, the limited laboratory infrastructure, and the absence of a reporting system could be contributing factors to underestimate the importance of nontuberculous mycobacteria in this setting. We recommend that nontuberculous mycobacteria identification should be considered for public health intervention.https://revistas.unilibre.edu.co/index.php/iJEPH/article/view/5449nontuberculous mycobacteriapulmonary diseasemycobacterium spptuberculosis treatment |
| spellingShingle | Luis Eduardo Delgado Daniela Rocío Escobar Diana Marcela Hoyos Lucy Luna Robinson Pacheco López Beatriz E. Ferro Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 Interdisciplinary Journal of Epidemiology and Public Health nontuberculous mycobacteria pulmonary disease mycobacterium spp tuberculosis treatment |
| title | Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 |
| title_full | Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 |
| title_fullStr | Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 |
| title_full_unstemmed | Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 |
| title_short | Nontuberculous mycobacteria in patients registered in a tuberculosis control program in Southwestern Colombia, 2014-2017 |
| title_sort | nontuberculous mycobacteria in patients registered in a tuberculosis control program in southwestern colombia 2014 2017 |
| topic | nontuberculous mycobacteria pulmonary disease mycobacterium spp tuberculosis treatment |
| url | https://revistas.unilibre.edu.co/index.php/iJEPH/article/view/5449 |
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