A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images

Accurate optic disc (OD) segmentation and fovea detection in retinal fundus images are crucial for diagnosis in ophthalmology. We propose a robust and broadly applicable algorithm for automated, robust, reliable and consistent fovea detection based on OD segmentation. The OD segmentation is performe...

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Main Authors: Rust Caterina, Häger Stephanie, Traulsen Nadine, Modersitzki Jan
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2017-0113
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author Rust Caterina
Häger Stephanie
Traulsen Nadine
Modersitzki Jan
author_facet Rust Caterina
Häger Stephanie
Traulsen Nadine
Modersitzki Jan
author_sort Rust Caterina
collection DOAJ
description Accurate optic disc (OD) segmentation and fovea detection in retinal fundus images are crucial for diagnosis in ophthalmology. We propose a robust and broadly applicable algorithm for automated, robust, reliable and consistent fovea detection based on OD segmentation. The OD segmentation is performed with morphological operations and Fuzzy C Means Clustering combined with iterative thresholding on a foreground segmentation. The fovea detection is based on a vessel segmentation via morphological operations and uses the resulting OD segmentation to determine multiple regions of interest. The fovea is determined from the largest, vessel-free candidate region. We have tested the novel method on a total of 190 images from three publicly available databases DRIONS, Drive and HRF. Compared to results of two human experts for DRIONS database, our OD segmentation yielded a dice coefficient of 0.83. Note that missing ground truth and expert variability is an issue. The new scheme achieved an overall success rate of 99.44% for OD detection and an overall success rate of 96.25% for fovea detection, which is superior to state-of-the-art approaches.
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spelling doaj.art-f3cbe0409b6f42afb728e70e5e9118cb2023-04-11T17:07:14ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042017-09-013253353710.1515/cdbme-2017-0113cdbme-2017-0113A robust algorithm for optic disc segmentation and fovea detection in retinal fundus imagesRust Caterina0Häger Stephanie1Traulsen Nadine2Modersitzki Jan3Institute of Mathematics and Image Computing, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, GermanyInstitute of Mathematics and Image Computing, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, GermanyFraunhofer Institute for Medical Image Computing MEVIS, Maria-Goeppert-Straße 3, 23562 Lübeck, GermanyInstitute of Mathematics and Image Computing, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, GermanyAccurate optic disc (OD) segmentation and fovea detection in retinal fundus images are crucial for diagnosis in ophthalmology. We propose a robust and broadly applicable algorithm for automated, robust, reliable and consistent fovea detection based on OD segmentation. The OD segmentation is performed with morphological operations and Fuzzy C Means Clustering combined with iterative thresholding on a foreground segmentation. The fovea detection is based on a vessel segmentation via morphological operations and uses the resulting OD segmentation to determine multiple regions of interest. The fovea is determined from the largest, vessel-free candidate region. We have tested the novel method on a total of 190 images from three publicly available databases DRIONS, Drive and HRF. Compared to results of two human experts for DRIONS database, our OD segmentation yielded a dice coefficient of 0.83. Note that missing ground truth and expert variability is an issue. The new scheme achieved an overall success rate of 99.44% for OD detection and an overall success rate of 96.25% for fovea detection, which is superior to state-of-the-art approaches.https://doi.org/10.1515/cdbme-2017-0113optic disc segmentationfovea detection
spellingShingle Rust Caterina
Häger Stephanie
Traulsen Nadine
Modersitzki Jan
A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
Current Directions in Biomedical Engineering
optic disc segmentation
fovea detection
title A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
title_full A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
title_fullStr A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
title_full_unstemmed A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
title_short A robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
title_sort robust algorithm for optic disc segmentation and fovea detection in retinal fundus images
topic optic disc segmentation
fovea detection
url https://doi.org/10.1515/cdbme-2017-0113
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