Targeting cell cycle proteins in breast cancer cells with siRNA by using lipid-substituted polyethylenimines
The cell cycle proteins are key regulators of cell cycle progression whose de-regulation is one of the causes of breast cancer. RNA interference (RNAi) is an endogenous mechanism to regulate gene expression and it could serve as the basis of regulating aberrant proteins including cell cycle proteins...
Main Authors: | Manoj eParmar, Hamid M. Aliabadi, Parvin eMahdipoor, Cezary eKucharski, Robert eMaranchuk, Judith C Hugh, Hasan eUludag |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-02-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00014/full |
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