Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2

Hypothalamic CREB Regulates the Expression of Pomc-Processing Enzyme Pcsk2

Background: The hypothalamic proopiomelanocortin (Pomc) neurons act as first-order sensors of systemic energy stores, providing signals that regulate caloric intake and energy expenditure. In experimental obesity, dietary saturated fatty acids affect Pomc endopeptidases (PCs), resulting in the abnor...

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Bibliographic Details
Main Authors: Ariane Maria Zanesco, Natalia F. Mendes, Daiane F. Engel, Rodrigo S. Gaspar, Davi Sidarta-Oliveira, José Donato, Licio A. Velloso
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
proopiomelanocortin
obesity
diet
saturated fatty acid
CREB
Online Access:https://www.mdpi.com/2073-4409/11/13/1996

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