Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis
Vestibular involvements have long been observed in otosclerotic patients. Among vestibular structures saccule has the closest anatomical proximity to the sclerotic foci, so it is the most prone vestibular structure to be affected during the otosclerosis process. The aim of this study was to investig...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2014-02-01
|
| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/4846 |
| _version_ | 1818359660289196032 |
|---|---|
| author | Amin Amali Parvane Mahdi Alireza Karimi Yazdi Mohammad Taghi Khorsandi Ashtiyani Nasrin Yazdani Varasteh Vakili Akram Pourbakht |
| author_facet | Amin Amali Parvane Mahdi Alireza Karimi Yazdi Mohammad Taghi Khorsandi Ashtiyani Nasrin Yazdani Varasteh Vakili Akram Pourbakht |
| author_sort | Amin Amali |
| collection | DOAJ |
| description | Vestibular involvements have long been observed in otosclerotic patients. Among vestibular structures saccule has the closest anatomical proximity to the sclerotic foci, so it is the most prone vestibular structure to be affected during the otosclerosis process. The aim of this study was to investigate the saccular function in patients suffering from otosclerosis, by means of Vestibular Evoked Myogenic Potential (VEMP). The material consisted of 30 otosclerosis patients and 20 control subjects. All participants underwent audiometric and VEMP testing. Analysis of tests results revealed that the mean values of Air-Conducted Pure Tone Average (AC-PTA) and Bone-Conducted Pure Tone Average (BC-PTA) in patients were 45.28 ± 15.57 and 19.68 ± 10.91, respectively and calculated 4 frequencies Air Bone Gap (ABG) was 25.64 ± 9.95. The VEMP response was absent in 14 (28.57%) otosclerotic ears. A statistically significant increase in latency of the p13 was found in the affected ears (P=0.004), differences in n23 latency did not reach a statistically significant level (P=0.112). Disparities in amplitude of p13-n23 in between two study groups was statistically meaningful (P=0.009), indicating that the patients with otosclerosis had lower amplitudes. This study tends to suggest that due to the direct biotoxic effect of the materials released from the otosclerosis foci on saccular receptors, there might be a possibility of vestibular dysfunction in otosclerotic patients. |
| first_indexed | 2024-12-13T20:48:25Z |
| format | Article |
| id | doaj.art-f3cd6d8b54e942748600f9b1e25686fb |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-13T20:48:25Z |
| publishDate | 2014-02-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-f3cd6d8b54e942748600f9b1e25686fb2022-12-21T23:31:56ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942014-02-015224799Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential AnalysisAmin Amali0Parvane Mahdi1Alireza Karimi Yazdi2Mohammad Taghi Khorsandi Ashtiyani3Nasrin Yazdani4Varasteh Vakili5Akram Pourbakht6Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Audiology, Rehabilitation Research Center, Iran University of Medical Sciences, Tehran, Iran.Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.Otorhinolaryngology Research Center, Amir Alam Educational Hospital, Tehran University of Medical Sciences, Tehran, Iran.Otorhinolaryngology Research Center, Amir Alam Educational Hospital, Tehran University of Medical Sciences, Tehran, Iran.Otorhinolaryngology Research Center, Imam Khomeini Educational Complex Hospital, Valieasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Audiology, Rehabilitation Research Center, Iran University of Medical Sciences, Tehran, Iran.Vestibular involvements have long been observed in otosclerotic patients. Among vestibular structures saccule has the closest anatomical proximity to the sclerotic foci, so it is the most prone vestibular structure to be affected during the otosclerosis process. The aim of this study was to investigate the saccular function in patients suffering from otosclerosis, by means of Vestibular Evoked Myogenic Potential (VEMP). The material consisted of 30 otosclerosis patients and 20 control subjects. All participants underwent audiometric and VEMP testing. Analysis of tests results revealed that the mean values of Air-Conducted Pure Tone Average (AC-PTA) and Bone-Conducted Pure Tone Average (BC-PTA) in patients were 45.28 ± 15.57 and 19.68 ± 10.91, respectively and calculated 4 frequencies Air Bone Gap (ABG) was 25.64 ± 9.95. The VEMP response was absent in 14 (28.57%) otosclerotic ears. A statistically significant increase in latency of the p13 was found in the affected ears (P=0.004), differences in n23 latency did not reach a statistically significant level (P=0.112). Disparities in amplitude of p13-n23 in between two study groups was statistically meaningful (P=0.009), indicating that the patients with otosclerosis had lower amplitudes. This study tends to suggest that due to the direct biotoxic effect of the materials released from the otosclerosis foci on saccular receptors, there might be a possibility of vestibular dysfunction in otosclerotic patients.https://acta.tums.ac.ir/index.php/acta/article/view/4846OtosclerosisSacculeBone Conducted-VestibularMyogenic |
| spellingShingle | Amin Amali Parvane Mahdi Alireza Karimi Yazdi Mohammad Taghi Khorsandi Ashtiyani Nasrin Yazdani Varasteh Vakili Akram Pourbakht Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis Acta Medica Iranica Otosclerosis Saccule Bone Conducted-Vestibular Myogenic |
| title | Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis |
| title_full | Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis |
| title_fullStr | Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis |
| title_full_unstemmed | Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis |
| title_short | Saccular Function in Otosclerosis Patients: Bone Conducted-Vestibular Evoked Myogenic Potential Analysis |
| title_sort | saccular function in otosclerosis patients bone conducted vestibular evoked myogenic potential analysis |
| topic | Otosclerosis Saccule Bone Conducted-Vestibular Myogenic |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/4846 |
| work_keys_str_mv | AT aminamali saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT parvanemahdi saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT alirezakarimiyazdi saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT mohammadtaghikhorsandiashtiyani saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT nasrinyazdani saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT varastehvakili saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis AT akrampourbakht saccularfunctioninotosclerosispatientsboneconductedvestibularevokedmyogenicpotentialanalysis |