Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery

Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery

The objective of the present study was to develop, optimize, and evaluate rotigotine-loaded chitosan nanoparticles (RNPs) for nose-to-brain delivery. Rotigotine-loaded chitosan nanoparticles were prepared by the ionic gelation method and optimized for various parameters such as the effect of chitosa...

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Bibliographic Details
Main Authors: Angeline Shak. Tzeyung, Shadab Md, Subrat Kumar Bhattamisra, Thiagarajan Madheswaran, Nabil A. Alhakamy, Hibah M. Aldawsari, Ammu K. Radhakrishnan
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceutics
Subjects:
chitosan
nanoparticles
nose to brain
Parkinson disease
rotigotine
Online Access:http://www.mdpi.com/1999-4923/11/1/26

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