Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents
Abstract Background Although several studies evaluated the relationship between individual dietary antioxidants and metabolic health conditions, data on the association between dietary total antioxidant capacity and metabolic health among children and adolescents is limited. This study investigated...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | Nutrition Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12937-022-00806-9 |
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| author | Sobhan Mohammadi Keyhan Lotfi Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei |
| author_facet | Sobhan Mohammadi Keyhan Lotfi Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei |
| author_sort | Sobhan Mohammadi |
| collection | DOAJ |
| description | Abstract Background Although several studies evaluated the relationship between individual dietary antioxidants and metabolic health conditions, data on the association between dietary total antioxidant capacity and metabolic health among children and adolescents is limited. This study investigated the relationship between dietary total antioxidant capacity and metabolic health status in Iranian overweight/obese adolescents. Methods This cross-sectional study was conducted on 203 overweight/obese adolescents. Dietary intakes were evaluated by a validated food frequency questionnaire. Ferric Reducing-Antioxidant Power (FRAP) was considered to indicate dietary total antioxidant capacity. Anthropometric parameters and blood pressure status were measured. Fasting blood samples were obtained to determine circulating insulin, glucose, and lipid profile. Two different methods (modified International Diabetes Federation (IDF) criteria and IDF criteria along with insulin resistance) were applied to classify participants as metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO). Results According to IDF and IDF/HOMA definitions, a total of 79 (38.9%) and 67 (33.0%) adolescents were respectively defined as MUO. Considering IDF criteria, the highest tertile of FRAP was related to lower odds of being MUO in the maximally-adjusted model (OR: 0.40; 95%CI: 0.16–0.96), compared to the lowest tertile. However, based on the IDF/HOMA-IR criteria, no significant relation was found between FRAP and odds of MUO (OR: 0.49; 95%CI: 0.19–1.23) after considering all possible confounders. Conclusions Adolescents with higher intakes of dietary antioxidants have a lower possibility of being MUO based on IDF criteria. However, no substantial relation was found considering HOMA-IR/IDF definition. Further prospective cohort studies need to be done to confirm these findings. |
| first_indexed | 2024-04-13T06:05:40Z |
| format | Article |
| id | doaj.art-f3d3032256c644ba95404d9383b44edf |
| institution | Directory Open Access Journal |
| issn | 1475-2891 |
| language | English |
| last_indexed | 2024-04-13T06:05:40Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition Journal |
| spelling | doaj.art-f3d3032256c644ba95404d9383b44edf2022-12-22T02:59:16ZengBMCNutrition Journal1475-28912022-08-012111910.1186/s12937-022-00806-9Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescentsSobhan Mohammadi0Keyhan Lotfi1Saeideh Mirzaei2Ali Asadi3Masoumeh Akhlaghi4Parvane Saneei5Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Students’ Research Committee, Isfahan University of Medical SciencesDepartment of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesDepartment of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical SciencesDepartment of Exercise Physiology, School of Physical Education and Sport Sciences, University of TehranDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical SciencesDepartment of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical SciencesAbstract Background Although several studies evaluated the relationship between individual dietary antioxidants and metabolic health conditions, data on the association between dietary total antioxidant capacity and metabolic health among children and adolescents is limited. This study investigated the relationship between dietary total antioxidant capacity and metabolic health status in Iranian overweight/obese adolescents. Methods This cross-sectional study was conducted on 203 overweight/obese adolescents. Dietary intakes were evaluated by a validated food frequency questionnaire. Ferric Reducing-Antioxidant Power (FRAP) was considered to indicate dietary total antioxidant capacity. Anthropometric parameters and blood pressure status were measured. Fasting blood samples were obtained to determine circulating insulin, glucose, and lipid profile. Two different methods (modified International Diabetes Federation (IDF) criteria and IDF criteria along with insulin resistance) were applied to classify participants as metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO). Results According to IDF and IDF/HOMA definitions, a total of 79 (38.9%) and 67 (33.0%) adolescents were respectively defined as MUO. Considering IDF criteria, the highest tertile of FRAP was related to lower odds of being MUO in the maximally-adjusted model (OR: 0.40; 95%CI: 0.16–0.96), compared to the lowest tertile. However, based on the IDF/HOMA-IR criteria, no significant relation was found between FRAP and odds of MUO (OR: 0.49; 95%CI: 0.19–1.23) after considering all possible confounders. Conclusions Adolescents with higher intakes of dietary antioxidants have a lower possibility of being MUO based on IDF criteria. However, no substantial relation was found considering HOMA-IR/IDF definition. Further prospective cohort studies need to be done to confirm these findings.https://doi.org/10.1186/s12937-022-00806-9Dietary total antioxidant capacityObesityMetabolically health statusAdolescentsChildren |
| spellingShingle | Sobhan Mohammadi Keyhan Lotfi Saeideh Mirzaei Ali Asadi Masoumeh Akhlaghi Parvane Saneei Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents Nutrition Journal Dietary total antioxidant capacity Obesity Metabolically health status Adolescents Children |
| title | Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| title_full | Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| title_fullStr | Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| title_full_unstemmed | Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| title_short | Dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| title_sort | dietary total antioxidant capacity in relation to metabolic health status in overweight and obese adolescents |
| topic | Dietary total antioxidant capacity Obesity Metabolically health status Adolescents Children |
| url | https://doi.org/10.1186/s12937-022-00806-9 |
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