Type II NKT cells in inflammation, autoimmunity, microbial immunity and cancer

Natural killer T cells (NKT) recognize self and microbial lipid antigens presented by non-polymorphic CD1d molecules. Two major NKT cell subsets, type I and II, express different types of antigen receptors (TCR) with distinct mode of CD1d/lipid recognition. Though, type II NKT cells are less frequen...

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Bibliographic Details
Main Authors: Idania eMarrero, Randle eWare, Vipin eKumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00316/full